On the Occurrence and Multimerization of Two-Polypeptide Phage Endolysins Encoded in Single Genes

On the Occurrence and Multimerization of Two-Polypeptide Phage Endolysins Encoded in Single Genes

ABSTRACT Bacteriophages (phages) and other viruses are extremely efficient in packing their genetic information, with several described cases of overlapping genes encoded in different open reading frames (ORFs). While less frequently reported, specific cases exist in which two overlapping ORFs are i...

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Bibliographic Details
Main Authors: Daniela Pinto, Raquel Gonçalo, Mariana Louro, Marta Sousa Silva, Guillem Hernandez, Tiago N. Cordeiro, Carlos Cordeiro, Carlos São-José
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
bacteriophage
endolysin
protein isoforms
cell wall
protein complex
bacteriophage lysis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01037-22

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