Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]

Africa bears the brunt of many of the world’s most devastating human and animal infectious diseases, a good number of which have no licensed or effective vaccines available. The continent’s potential to generate novel interventions against these global health threats is however largely untapped. Str...

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Main Authors: George M. Warimwe, Jyothi Purushotham, Brian D. Perry, Adrian V.S. Hill, Sarah C. Gilbert, Baptiste Dungu, Bryan Charleston
Format: Article
Language:English
Published: F1000 Research Ltd 2018-07-01
Series:AAS Open Research
Online Access:https://aasopenresearch.org/articles/1-18/v1
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author George M. Warimwe
Jyothi Purushotham
Brian D. Perry
Adrian V.S. Hill
Sarah C. Gilbert
Baptiste Dungu
Bryan Charleston
author_facet George M. Warimwe
Jyothi Purushotham
Brian D. Perry
Adrian V.S. Hill
Sarah C. Gilbert
Baptiste Dungu
Bryan Charleston
author_sort George M. Warimwe
collection DOAJ
description Africa bears the brunt of many of the world’s most devastating human and animal infectious diseases, a good number of which have no licensed or effective vaccines available. The continent’s potential to generate novel interventions against these global health threats is however largely untapped. Strengthening Africa’s vaccine research and development (R&D) sector could accelerate discovery, development and deployment of effective countermeasures against locally prevalent infectious diseases, many of which are neglected and have the capacity to spread to new geographical settings. Here, we review Africa’s human and veterinary vaccine R&D sectors and identify key areas that should be prioritized for investment, and synergies that could be exploited from Africa’s veterinary vaccine industry, which is surprisingly strong and has close parallels with human vaccine R&D.
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spelling doaj.art-8b79fc8e73f14dfd933325205521180a2023-09-03T00:21:27ZengF1000 Research LtdAAS Open Research2515-93212018-07-01110.12688/aasopenres.12877.113943Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]George M. Warimwe0Jyothi Purushotham1Brian D. Perry2Adrian V.S. Hill3Sarah C. Gilbert4Baptiste Dungu5Bryan Charleston6Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, KenyaThe Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UKThe Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UKThe Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UKThe Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UKM.C.I. Santé Animale, Mohammedia, 28810, MoroccoThe Pirbright Institute, Woking, GU24 0NF, UKAfrica bears the brunt of many of the world’s most devastating human and animal infectious diseases, a good number of which have no licensed or effective vaccines available. The continent’s potential to generate novel interventions against these global health threats is however largely untapped. Strengthening Africa’s vaccine research and development (R&D) sector could accelerate discovery, development and deployment of effective countermeasures against locally prevalent infectious diseases, many of which are neglected and have the capacity to spread to new geographical settings. Here, we review Africa’s human and veterinary vaccine R&D sectors and identify key areas that should be prioritized for investment, and synergies that could be exploited from Africa’s veterinary vaccine industry, which is surprisingly strong and has close parallels with human vaccine R&D.https://aasopenresearch.org/articles/1-18/v1
spellingShingle George M. Warimwe
Jyothi Purushotham
Brian D. Perry
Adrian V.S. Hill
Sarah C. Gilbert
Baptiste Dungu
Bryan Charleston
Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]
AAS Open Research
title Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]
title_full Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]
title_fullStr Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]
title_full_unstemmed Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]
title_short Tackling human and animal health threats through innovative vaccinology in Africa [version 1; peer review: 2 approved]
title_sort tackling human and animal health threats through innovative vaccinology in africa version 1 peer review 2 approved
url https://aasopenresearch.org/articles/1-18/v1
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