E-peptides control bioavailability of IGF-1.
Insulin-like growth factor 1 (IGF-1) is a potent cytoprotective growth factor that has attracted considerable attention as a promising therapeutic agent. Transgenic over-expression of IGF-1 propeptides facilitates protection and repair in a broad range of tissues, although transgenic mice over-expre...
Main Authors: | Marianne Smedegaard Hede, Ekaterina Salimova, Agnieszka Piszczek, Emarald Perlas, Nadine Winn, Tommaso Nastasi, Nadia Rosenthal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3519493?pdf=render |
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