E-peptides control bioavailability of IGF-1.

E-peptides control bioavailability of IGF-1.

Insulin-like growth factor 1 (IGF-1) is a potent cytoprotective growth factor that has attracted considerable attention as a promising therapeutic agent. Transgenic over-expression of IGF-1 propeptides facilitates protection and repair in a broad range of tissues, although transgenic mice over-expre...

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Bibliographic Details
Main Authors: Marianne Smedegaard Hede, Ekaterina Salimova, Agnieszka Piszczek, Emarald Perlas, Nadine Winn, Tommaso Nastasi, Nadia Rosenthal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519493?pdf=render

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