Viroid Pathogenicity: One Process, Many Faces

Despite the non-coding nature of their small RNA genomes, the visible symptoms of viroid infection resemble those associated with many plant virus diseases. Recent evidence indicates that viroid-derived small RNAs acting through host RNA silencing pathways play a key role in viroid pathogenicity. Ho...

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Bibliographic Details
Main Authors: Rosemarie W. Hammond, Robert A. Owens
Format: Article
Language:English
Published: MDPI AG 2009-09-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/1/2/298/
Description
Summary:Despite the non-coding nature of their small RNA genomes, the visible symptoms of viroid infection resemble those associated with many plant virus diseases. Recent evidence indicates that viroid-derived small RNAs acting through host RNA silencing pathways play a key role in viroid pathogenicity. Host responses to viroid infection are complex, involving signaling cascades containing host-encoded protein kinases and crosstalk between hormonal and defense-signaling pathways. Studies of viroid-host interaction in the context of entire biochemical or developmental pathways are just beginning, and many working hypotheses have yet to be critically tested.
ISSN:1999-4915