Optical Coherence Tomography: Clinical Applications in Medical Practice

Optical Coherence Tomography (OCT) is a success story of scientific and technological co-operation between a physicist and a clinician. The concept of cross-sectional imaging revolutionalized the applicability of OCT in the medical profession. OCT is a non-contact, topographic, biomicroscopic device...

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Main Authors: Abdullah Al-Mujaini, Upender K. Wali, Sitara Azeem
Format: Article
Language:English
Published: Oman Medical Specialty Board 2013-03-01
Series:Oman Medical Journal
Subjects:
Online Access:http://www.omjournal.org/fultext_PDF.aspx?DetailsID=348&type=fultext
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author Abdullah Al-Mujaini
Upender K. Wali
Sitara Azeem
author_facet Abdullah Al-Mujaini
Upender K. Wali
Sitara Azeem
author_sort Abdullah Al-Mujaini
collection DOAJ
description Optical Coherence Tomography (OCT) is a success story of scientific and technological co-operation between a physicist and a clinician. The concept of cross-sectional imaging revolutionalized the applicability of OCT in the medical profession. OCT is a non-contact, topographic, biomicroscopic device that provides high resolution, cross-sectional digital images of live biological tissues in vivo and in real time. OCT is based on the property of tissues to reflect and backscatter light involving low-coherence interferometry. The spatial resolution of as little as 3 microns or even less has allowed us to study tissues almost at a cellular level. Overall, OCT is an invaluable adjunct in the diagnosis and follow up of many diseases of both anterior and posterior segments of the eye, primarily or secondary to systemic diseases. The digitalization and advanced software has made it possible to store and retrieve huge patient data for patient services, clinical applications and academic research. OCT has revolutionized the sensitivity and specificity of diagnosis, follow up and response to treatment in almost all fields of clinical practice involving primary ocular pathologies and secondary ocular manifestations in systemic diseases like diabetes mellitus, hypertension, vascular and neurological diseases, thus benefitting non-ophthalmologists as well. Systemically, OCT is proving to be a helpful tool in substantiating early diagnosis in diseases like multiple sclerosis and drug induced retinopathies by detecting early changes in morphology of the retinal nerve fiber layer.
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spelling doaj.art-8b885663ed0a422dab88258f8503236f2022-12-22T01:47:50ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042013-03-012828691Optical Coherence Tomography: Clinical Applications in Medical PracticeAbdullah Al-MujainiUpender K. WaliSitara AzeemOptical Coherence Tomography (OCT) is a success story of scientific and technological co-operation between a physicist and a clinician. The concept of cross-sectional imaging revolutionalized the applicability of OCT in the medical profession. OCT is a non-contact, topographic, biomicroscopic device that provides high resolution, cross-sectional digital images of live biological tissues in vivo and in real time. OCT is based on the property of tissues to reflect and backscatter light involving low-coherence interferometry. The spatial resolution of as little as 3 microns or even less has allowed us to study tissues almost at a cellular level. Overall, OCT is an invaluable adjunct in the diagnosis and follow up of many diseases of both anterior and posterior segments of the eye, primarily or secondary to systemic diseases. The digitalization and advanced software has made it possible to store and retrieve huge patient data for patient services, clinical applications and academic research. OCT has revolutionized the sensitivity and specificity of diagnosis, follow up and response to treatment in almost all fields of clinical practice involving primary ocular pathologies and secondary ocular manifestations in systemic diseases like diabetes mellitus, hypertension, vascular and neurological diseases, thus benefitting non-ophthalmologists as well. Systemically, OCT is proving to be a helpful tool in substantiating early diagnosis in diseases like multiple sclerosis and drug induced retinopathies by detecting early changes in morphology of the retinal nerve fiber layer.http://www.omjournal.org/fultext_PDF.aspx?DetailsID=348&type=fultextOptical Coherence TomographyBiomicroscopyInterferometry.
spellingShingle Abdullah Al-Mujaini
Upender K. Wali
Sitara Azeem
Optical Coherence Tomography: Clinical Applications in Medical Practice
Oman Medical Journal
Optical Coherence Tomography
Biomicroscopy
Interferometry.
title Optical Coherence Tomography: Clinical Applications in Medical Practice
title_full Optical Coherence Tomography: Clinical Applications in Medical Practice
title_fullStr Optical Coherence Tomography: Clinical Applications in Medical Practice
title_full_unstemmed Optical Coherence Tomography: Clinical Applications in Medical Practice
title_short Optical Coherence Tomography: Clinical Applications in Medical Practice
title_sort optical coherence tomography clinical applications in medical practice
topic Optical Coherence Tomography
Biomicroscopy
Interferometry.
url http://www.omjournal.org/fultext_PDF.aspx?DetailsID=348&type=fultext
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AT upenderkwali opticalcoherencetomographyclinicalapplicationsinmedicalpractice
AT sitaraazeem opticalcoherencetomographyclinicalapplicationsinmedicalpractice