Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas
Objective We report the effectiveness and safety of ultrasound (US) guided microwave ablation (MWA) treatment of parathyroid adenomas. Materials and Methods A total of 35 patients underwent US-guided MWA therapy of parathyroid adenomas. Before the procedure, blood parathyroid hormone (PTH...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-01-01
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| Series: | The Arab Journal of Interventional Radiology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764436 |
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| author | Furkan Ertürk Urfali Bünyamin Aydin Sezgin Zeren Güven Barış Cansu Mustafa Cem Algin Mehmet Korkmaz |
| author_facet | Furkan Ertürk Urfali Bünyamin Aydin Sezgin Zeren Güven Barış Cansu Mustafa Cem Algin Mehmet Korkmaz |
| author_sort | Furkan Ertürk Urfali |
| collection | DOAJ |
| description | Objective We report the effectiveness and safety of ultrasound (US) guided microwave ablation (MWA) treatment of parathyroid adenomas.
Materials and Methods A total of 35 patients underwent US-guided MWA therapy of parathyroid adenomas. Before the procedure, blood parathyroid hormone (PTH; mean: 202.32 ± 158.46 ng/L) level, calcium (mean: 11.65 ± 0.53 mg/dL) level, and parathyroid adenoma volume (mean: 1.76 ± 0.73 cm3) were recorded. Blood parameters and US-guided follow-up evaluations were performed at 1 and 3 months after the procedure.
Results Technical success was 91% for the first session. There was a statistically significant decrease in parathyroid adenoma size and calcium and PTH levels at 3 months of follow-up (p < 0.001). A perfect positive correlation (r: 0.927; p < 0.001) was found between the ablation time and the adenoma size. Transient vocal cord paralysis occurred in two (5.7%) patients and short-term (<2 hours) local pain occurred in four (11.4%) patients after the procedure.
Conclusion US-guided MWA is effective in the treatment of parathyroid adenomas with low complication risk. Our preliminary results showed that MWA treatment resulted in an effective improvement in blood tests and adenoma size. |
| first_indexed | 2024-03-13T08:18:48Z |
| format | Article |
| id | doaj.art-8b88ecb4a5fe43628cc5e27826b90818 |
| institution | Directory Open Access Journal |
| issn | 2542-7075 2542-7083 |
| language | English |
| last_indexed | 2024-03-13T08:18:48Z |
| publishDate | 2023-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | The Arab Journal of Interventional Radiology |
| spelling | doaj.art-8b88ecb4a5fe43628cc5e27826b908182023-05-31T12:35:51ZengThieme Medical and Scientific Publishers Pvt. Ltd.The Arab Journal of Interventional Radiology2542-70752542-70832023-01-01070103904310.1055/s-0043-1764436Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid AdenomasFurkan Ertürk Urfali0Bünyamin Aydin1Sezgin Zeren2Güven Barış Cansu3Mustafa Cem Algin4Mehmet Korkmaz5Deparment of Interventional Radiology, Kutahya Health Science University, Istiklal, Kutahya, TurkeyDeparment of Endocrinology and Metabolic Diseases, Kutahya Health Science University, Istiklal, Kutahya, TurkeyDeparment of General Surgery, Kutahya Health Science University, Istiklal, Kutahya, TurkeyDeparment of Endocrinology and Metabolic Diseases, Kutahya Health Science University, Istiklal, Kutahya, TurkeyDeparment of General Surgery, Kutahya Health Science University, Istiklal, Kutahya, TurkeyDeparment of Interventional Radiology, Kutahya Health Science University, Istiklal, Kutahya, TurkeyObjective We report the effectiveness and safety of ultrasound (US) guided microwave ablation (MWA) treatment of parathyroid adenomas. Materials and Methods A total of 35 patients underwent US-guided MWA therapy of parathyroid adenomas. Before the procedure, blood parathyroid hormone (PTH; mean: 202.32 ± 158.46 ng/L) level, calcium (mean: 11.65 ± 0.53 mg/dL) level, and parathyroid adenoma volume (mean: 1.76 ± 0.73 cm3) were recorded. Blood parameters and US-guided follow-up evaluations were performed at 1 and 3 months after the procedure. Results Technical success was 91% for the first session. There was a statistically significant decrease in parathyroid adenoma size and calcium and PTH levels at 3 months of follow-up (p < 0.001). A perfect positive correlation (r: 0.927; p < 0.001) was found between the ablation time and the adenoma size. Transient vocal cord paralysis occurred in two (5.7%) patients and short-term (<2 hours) local pain occurred in four (11.4%) patients after the procedure. Conclusion US-guided MWA is effective in the treatment of parathyroid adenomas with low complication risk. Our preliminary results showed that MWA treatment resulted in an effective improvement in blood tests and adenoma size.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764436ablationparathyroidultrasound |
| spellingShingle | Furkan Ertürk Urfali Bünyamin Aydin Sezgin Zeren Güven Barış Cansu Mustafa Cem Algin Mehmet Korkmaz Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas The Arab Journal of Interventional Radiology ablation parathyroid ultrasound |
| title | Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas |
| title_full | Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas |
| title_fullStr | Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas |
| title_full_unstemmed | Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas |
| title_short | Effectiveness and Safety of Microwave Ablation Therapy in Parathyroid Adenomas |
| title_sort | effectiveness and safety of microwave ablation therapy in parathyroid adenomas |
| topic | ablation parathyroid ultrasound |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764436 |
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