Severe Hypertriglyceridaemia and Chylomicronaemia Syndrome—Causes, Clinical Presentation, and Therapeutic Options

Severe Hypertriglyceridaemia and Chylomicronaemia Syndrome—Causes, Clinical Presentation, and Therapeutic Options

We have reviewed the genetic basis of chylomicronaemia, the difference between monogenic and polygenic hypertriglyceridaemia, its effects on pancreatic, cardiovascular, and microvascular complications, and current and potential future pharmacotherapies. Severe hypertriglyceridaemia (TG > 10 mmol/...

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Bibliographic Details
Main Authors: Bilal Bashir, Jan H. Ho, Paul Downie, Paul Hamilton, Gordon Ferns, Dev Datta, Jaimini Cegla, Anthony S. Wierzbicki, Charlotte Dawson, Fiona Jenkinson, Hannah Delaney, Michael Mansfield, Yee Teoh, Zosia Miedzybrodzka, Haya Haso, Paul N. Durrington, Handrean Soran
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Metabolites
Subjects:
hypertriglyceridaemia
chylomicronaemia syndrome
pancreatitis
atherosclerosis
microvascular complications
volanesorsen
Online Access:https://www.mdpi.com/2218-1989/13/5/621

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