Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology

Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology

ABSTRACTType III interferons (IFN-λ) are antiviral and immunomodulatory cytokines that have been best characterized in respiratory and gastrointestinal infections, but the effects of IFN-λ against skin infections have not been extensively investigated. We sought to define the skin-specific effects o...

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Bibliographic Details
Main Authors: Drake T. Philip, Nigel M. Goins, Nicholas J. Catanzaro, Ichiro Misumi, Jason K. Whitmire, Hannah M. Atkins, Helen M. Lazear
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mBio
Subjects:
herpes simplex virus
interferon lambda
skin
neutrophils
keratinocyte
Online Access:https://journals.asm.org/doi/10.1128/mbio.02623-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02623-23

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