Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up
Objective: Recurrence and scar formation are the key leftover problems in the treatment of verrucous epidermal nevus (VEN). The objective of this study was to assess the long-term efficacy of bleomycin with triamcinolone acetonide in reducing the recurrence of VEN and scar formation after treatment....
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Turkish Journal of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.turkjplastsurg.org/article.asp?issn=1300-6878;year=2024;volume=32;issue=1;spage=6;epage=11;aulast=Luo |
| _version_ | 1797221636746772480 |
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| author | Quan-Feng Luo |
| author_facet | Quan-Feng Luo |
| author_sort | Quan-Feng Luo |
| collection | DOAJ |
| description | Objective: Recurrence and scar formation are the key leftover problems in the treatment of verrucous epidermal nevus (VEN). The objective of this study was to assess the long-term efficacy of bleomycin with triamcinolone acetonide in reducing the recurrence of VEN and scar formation after treatment. Methods: Bleomycin and triamcinolone were injected percutaneously into the lesion, and the drug was evenly distributed in the lesion. Several treatment courses were carried out according to the size and hyperplasia of the lesion. Necessary laser treatment was performed. Patients were followed up for 2–5 years. Results: The results showed that 83% of the patients were cured. The recurrence rate was 17%. The recurrence was localized and accounted for 3%–6% of the original lesion area. Scar formation accounted for 3.4%. Other complications did not occur. The patients or his/her guardian were satisfied with the treatment effect. Conclusion: Bleomycin with triamcin acetonide can significantly improve the cure rate of VEN and reduce the recurrence rate and scar formation. This method is a good option for VEN treatment. |
| first_indexed | 2024-04-24T13:08:35Z |
| format | Article |
| id | doaj.art-8b9039cce82a40bd96669a88dfb88555 |
| institution | Directory Open Access Journal |
| issn | 2528-8644 |
| language | English |
| last_indexed | 2024-04-24T13:08:35Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Turkish Journal of Plastic Surgery |
| spelling | doaj.art-8b9039cce82a40bd96669a88dfb885552024-04-05T05:10:46ZengWolters Kluwer Medknow PublicationsTurkish Journal of Plastic Surgery2528-86442024-01-0132161110.4103/tjps.tjps_29_23Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-upQuan-Feng LuoObjective: Recurrence and scar formation are the key leftover problems in the treatment of verrucous epidermal nevus (VEN). The objective of this study was to assess the long-term efficacy of bleomycin with triamcinolone acetonide in reducing the recurrence of VEN and scar formation after treatment. Methods: Bleomycin and triamcinolone were injected percutaneously into the lesion, and the drug was evenly distributed in the lesion. Several treatment courses were carried out according to the size and hyperplasia of the lesion. Necessary laser treatment was performed. Patients were followed up for 2–5 years. Results: The results showed that 83% of the patients were cured. The recurrence rate was 17%. The recurrence was localized and accounted for 3%–6% of the original lesion area. Scar formation accounted for 3.4%. Other complications did not occur. The patients or his/her guardian were satisfied with the treatment effect. Conclusion: Bleomycin with triamcin acetonide can significantly improve the cure rate of VEN and reduce the recurrence rate and scar formation. This method is a good option for VEN treatment.http://www.turkjplastsurg.org/article.asp?issn=1300-6878;year=2024;volume=32;issue=1;spage=6;epage=11;aulast=Luobleomycinrecurrencescartriamcinoloneverrucous epidermal nevus |
| spellingShingle | Quan-Feng Luo Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up Turkish Journal of Plastic Surgery bleomycin recurrence scar triamcinolone verrucous epidermal nevus |
| title | Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up |
| title_full | Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up |
| title_fullStr | Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up |
| title_full_unstemmed | Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up |
| title_short | Bleomycin and triamcinolone for the treatment of verrucous epidermal nevus: Long-term follow-up |
| title_sort | bleomycin and triamcinolone for the treatment of verrucous epidermal nevus long term follow up |
| topic | bleomycin recurrence scar triamcinolone verrucous epidermal nevus |
| url | http://www.turkjplastsurg.org/article.asp?issn=1300-6878;year=2024;volume=32;issue=1;spage=6;epage=11;aulast=Luo |
| work_keys_str_mv | AT quanfengluo bleomycinandtriamcinoloneforthetreatmentofverrucousepidermalnevuslongtermfollowup |