GIPC proteins negatively modulate Plexind1 signaling during vascular development

GIPC proteins negatively modulate Plexind1 signaling during vascular development

Semaphorins (SEMAs) and their Plexin (PLXN) receptors are central regulators of metazoan cellular communication. SEMA-PLXND1 signaling plays important roles in cardiovascular, nervous, and immune system development, and cancer biology. However, little is known about the molecular mechanisms that mod...

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Bibliographic Details
Main Authors: Jorge Carretero-Ortega, Zinal Chhangawala, Shane Hunt, Carlos Narvaez, Javier Menéndez-González, Carl M Gay, Tomasz Zygmunt, Xiaochun Li, Jesús Torres-Vázquez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
angiogenesis
cell signaling
GIPC
PlexinD1
Zebrafish
Online Access:https://elifesciences.org/articles/30454

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