Epidemiological and microbiological profile of infective keratitis in Ahmedabad
Context : Study of patients attending tertiary care ophthalmology institute at Ahmedabad. Aims : To study the microbiological etiology and epidemiological factors associated with suppurative keratitis. Settings and Design : A total of 150 corneal scrapings were evaluated from patients presenting wit...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=267;epage=272;aulast=Tewari |
| _version_ | 1818932371858128896 |
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| author | Aarti Tewari Nidhi Sood Mahendra M Vegad Dipak C Mehta |
| author_facet | Aarti Tewari Nidhi Sood Mahendra M Vegad Dipak C Mehta |
| author_sort | Aarti Tewari |
| collection | DOAJ |
| description | Context : Study of patients attending tertiary care ophthalmology institute at Ahmedabad. Aims : To study the microbiological etiology and epidemiological factors associated with suppurative keratitis. Settings and Design : A total of 150 corneal scrapings were evaluated from patients presenting with corneal ulcers at a tertiary ophthalmology center, Ahmedabad from July 2007 to June 2008. Materials and Methods : Scrapings were subjected to Gram stain, potassium hydroxide preparation and culture for bacterial and fungal pathogens. Socio-demographic data and risk factors were recorded. Results : Ninety percent (135/150) people with corneal ulcers had trauma as predisposing factor for keratitis. Trauma due to wooden objects was the leading cause (46/135) followed by vegetable matter and stone injury (23/135). Microbial etiology was established in 59.3% (89/150) of scrapings. Out of 89 positive isolates, 65.1% (58/89) were bacterial while 34.9% (31/89) were fungal. Among the bacterial isolates, 60.3% (35/58) were Gram-positive cocci while 39.7% (23/58) were Gram-negative bacilli. The most common bacterial isolate was Staphylococus aureus (32.7%, 19/58) followed by coagulase-negative Staphylococci (25.8%, 15/58) and Pseudomonas (18.9%, 11/58). Among the 31 fungal pathogens, Aspergillus species was the most common (35.4%11/31), followed by Fusarium species (22.5%, 7/31). Conclusion : Trauma with wooden material is the most common predisposing factor for suppurative keratitis. Males were more affected than females. Bacterial ulcers were more common than fungal in areas in and around Ahmedabad. Staphylococcus aureus and Aspergillus were the commonest bacterial and fungal isolates respectively. Geographical variation persists in microbial etiology of suppurative keratitis. |
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| format | Article |
| id | doaj.art-8b95e008ba72492abb76313699bd5c93 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-20T04:31:26Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-8b95e008ba72492abb76313699bd5c932022-12-21T19:53:23ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892012-01-0160426727210.4103/0301-4738.98702Epidemiological and microbiological profile of infective keratitis in AhmedabadAarti TewariNidhi SoodMahendra M VegadDipak C MehtaContext : Study of patients attending tertiary care ophthalmology institute at Ahmedabad. Aims : To study the microbiological etiology and epidemiological factors associated with suppurative keratitis. Settings and Design : A total of 150 corneal scrapings were evaluated from patients presenting with corneal ulcers at a tertiary ophthalmology center, Ahmedabad from July 2007 to June 2008. Materials and Methods : Scrapings were subjected to Gram stain, potassium hydroxide preparation and culture for bacterial and fungal pathogens. Socio-demographic data and risk factors were recorded. Results : Ninety percent (135/150) people with corneal ulcers had trauma as predisposing factor for keratitis. Trauma due to wooden objects was the leading cause (46/135) followed by vegetable matter and stone injury (23/135). Microbial etiology was established in 59.3% (89/150) of scrapings. Out of 89 positive isolates, 65.1% (58/89) were bacterial while 34.9% (31/89) were fungal. Among the bacterial isolates, 60.3% (35/58) were Gram-positive cocci while 39.7% (23/58) were Gram-negative bacilli. The most common bacterial isolate was Staphylococus aureus (32.7%, 19/58) followed by coagulase-negative Staphylococci (25.8%, 15/58) and Pseudomonas (18.9%, 11/58). Among the 31 fungal pathogens, Aspergillus species was the most common (35.4%11/31), followed by Fusarium species (22.5%, 7/31). Conclusion : Trauma with wooden material is the most common predisposing factor for suppurative keratitis. Males were more affected than females. Bacterial ulcers were more common than fungal in areas in and around Ahmedabad. Staphylococcus aureus and Aspergillus were the commonest bacterial and fungal isolates respectively. Geographical variation persists in microbial etiology of suppurative keratitis.http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=267;epage=272;aulast=TewariApoptosisglaucomaintraocular pressureretinal ganglion cellsretinal ischemiatumor necrosis factor-alphaBranch retinal vein occlusionlaserLucentismacular edemaMicrobial etiologymucopurulent keratitissuppurative keratitis |
| spellingShingle | Aarti Tewari Nidhi Sood Mahendra M Vegad Dipak C Mehta Epidemiological and microbiological profile of infective keratitis in Ahmedabad Indian Journal of Ophthalmology Apoptosis glaucoma intraocular pressure retinal ganglion cells retinal ischemia tumor necrosis factor-alpha Branch retinal vein occlusion laser Lucentis macular edema Microbial etiology mucopurulent keratitis suppurative keratitis |
| title | Epidemiological and microbiological profile of infective keratitis in Ahmedabad |
| title_full | Epidemiological and microbiological profile of infective keratitis in Ahmedabad |
| title_fullStr | Epidemiological and microbiological profile of infective keratitis in Ahmedabad |
| title_full_unstemmed | Epidemiological and microbiological profile of infective keratitis in Ahmedabad |
| title_short | Epidemiological and microbiological profile of infective keratitis in Ahmedabad |
| title_sort | epidemiological and microbiological profile of infective keratitis in ahmedabad |
| topic | Apoptosis glaucoma intraocular pressure retinal ganglion cells retinal ischemia tumor necrosis factor-alpha Branch retinal vein occlusion laser Lucentis macular edema Microbial etiology mucopurulent keratitis suppurative keratitis |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=267;epage=272;aulast=Tewari |
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