BRCA1 mutation promotes sprouting angiogenesis in inflammatory cancer-associated fibroblast of triple-negative breast cancer

BRCA1 mutation promotes sprouting angiogenesis in inflammatory cancer-associated fibroblast of triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with inferior outcomes owing to its low treatment response and high invasiveness. Based on abundant cancer-associated fibroblasts (CAFs) and frequent mutation of breast cancer-associated 1 (BRCA1) in TNBC, the chara...

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Bibliographic Details
Main Authors: Chae Min Lee, Yeseong Hwang, Jae Woong Jeong, Minki Kim, Janghee Lee, Soong June Bae, Sung Gwe Ahn, Sungsoon Fang
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01768-5

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