Natural history of anal dysplasia in an HIV-infected clinical care cohort: estimates using multi-state Markov modeling.

Natural history of anal dysplasia in an HIV-infected clinical care cohort: estimates using multi-state Markov modeling.

(1) To model the natural history of anal neoplasia in HIV-infected patients using a 3-state Markov model of anal cancer pathogenesis, adjusting for cytology misclassification; and (2) to estimate the effects of selected time-varying covariates on transition probabilities.A retrospective cytology-bas...

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Bibliographic Details
Main Authors: William C Mathews, Wollelaw Agmas, Edward R Cachay, Bard C Cosman, Christopher Jackson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4125167?pdf=render

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