Detection of Platelet-Activating Antibodies Associated with Vaccine-Induced Thrombotic Thrombocytopenia by Flow Cytometry: An Italian Experience

Detection of Platelet-Activating Antibodies Associated with Vaccine-Induced Thrombotic Thrombocytopenia by Flow Cytometry: An Italian Experience

Rare cases of thrombocytopenia and thrombosis after anti-COVID-19 adenovirus-associated mRNA vaccines (VITT) due to platelet-activating anti-platelet-factor 4 (PF4)/polyanion antibodies have been reported. VITT laboratory diagnosis, similarly to heparin-induced thrombocytopenia (HIT) diagnosis, requ...

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Bibliographic Details
Main Authors: Francesca Cesari, Silvia Sorrentino, Anna Maria Gori, Angela Rogolino, Raimondo De Cristofaro, Betti Giusti, Elena Sticchi, Erica De Candia, Rossella Marcucci
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
vaccine-induced thrombocytopenia and thrombosis (VITT)
diagnosis
flow cytometry
HIPA
heparin-induced thrombocytopenia and thrombosis (HIT)
Online Access:https://www.mdpi.com/1999-4915/14/6/1133

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