Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats
This study was designed to induction of testicular degeneration syndrome (TDS) in male rats by cadmium chloride and identified the best concentration of induction for this syndrome. The effective dose of cadmium chloride (CdCl₂) was determined by used fifteen males rats and where divided into t...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Medicine, University of Kufa
2022-06-01
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| Series: | Kufa Journal for Veterinary Medical Sciences |
| Subjects: | |
| Online Access: | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/3709 |
| _version_ | 1797364094331781120 |
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| author | Nabeel M. N. Al-Sharafi Saja Mazin Radhi Alobaidy |
| author_facet | Nabeel M. N. Al-Sharafi Saja Mazin Radhi Alobaidy |
| author_sort | Nabeel M. N. Al-Sharafi |
| collection | DOAJ |
| description |
This study was designed to induction of testicular degeneration syndrome (TDS) in male rats by cadmium chloride and identified the best concentration of induction for this syndrome.
The effective dose of cadmium chloride (CdCl₂) was determined by used fifteen males rats and where divided into three equal groups treated with CdCl₂ in a concentration (1, 2 and 3)mg/kg B.W. I.P. one /week for two weeks. Later the experimental animals was scarified and testis was took for measuring the antioxidant parameters via evaluated of glutathione GSH, malondialdehyde MDA, catalse, albumin, fructose concentrations and aminotransferase activity (ALT and AST).
According to this result the lowest observed adverse effective dose (LOAEL) of cadmium chloride that induced testicular degeneration in male rats was found to be 1mg/kg B.W. I.p. one /week for two weeks.
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| first_indexed | 2024-03-08T16:30:24Z |
| format | Article |
| id | doaj.art-8b9d851f7c73424fbce9086deb8e6691 |
| institution | Directory Open Access Journal |
| issn | 2077-9798 2959-8478 |
| language | English |
| last_indexed | 2024-03-08T16:30:24Z |
| publishDate | 2022-06-01 |
| publisher | Faculty of Veterinary Medicine, University of Kufa |
| record_format | Article |
| series | Kufa Journal for Veterinary Medical Sciences |
| spelling | doaj.art-8b9d851f7c73424fbce9086deb8e66912024-01-06T10:11:38ZengFaculty of Veterinary Medicine, University of KufaKufa Journal for Veterinary Medical Sciences2077-97982959-84782022-06-0113110.36326/kjvs/2022/v13i13709Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino ratsNabeel M. N. Al-Sharafi0Saja Mazin Radhi Alobaidy Faculty of Veterinary medicine - University of Kufa This study was designed to induction of testicular degeneration syndrome (TDS) in male rats by cadmium chloride and identified the best concentration of induction for this syndrome. The effective dose of cadmium chloride (CdCl₂) was determined by used fifteen males rats and where divided into three equal groups treated with CdCl₂ in a concentration (1, 2 and 3)mg/kg B.W. I.P. one /week for two weeks. Later the experimental animals was scarified and testis was took for measuring the antioxidant parameters via evaluated of glutathione GSH, malondialdehyde MDA, catalse, albumin, fructose concentrations and aminotransferase activity (ALT and AST). According to this result the lowest observed adverse effective dose (LOAEL) of cadmium chloride that induced testicular degeneration in male rats was found to be 1mg/kg B.W. I.p. one /week for two weeks. https://journal.uokufa.edu.iq/index.php/kjvs/article/view/3709cadmium chloride testiculardegeneration |
| spellingShingle | Nabeel M. N. Al-Sharafi Saja Mazin Radhi Alobaidy Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats Kufa Journal for Veterinary Medical Sciences cadmium chloride testicular degeneration |
| title | Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats |
| title_full | Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats |
| title_fullStr | Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats |
| title_full_unstemmed | Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats |
| title_short | Induction of Testicular Degeneration syndrome via Cadmium Chloride in male Albino rats |
| title_sort | induction of testicular degeneration syndrome via cadmium chloride in male albino rats |
| topic | cadmium chloride testicular degeneration |
| url | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/3709 |
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