Association of Areca Nut Chewing With Risk of Erectile Dysfunction
Introduction: Areca nut chewing has been shown to increase the risk of cardiovascular disease, but its association with erectile dysfunction (ED) has not been investigated. Aim: To investigate the association between areca nut chewing and risk of ED. Methods: Consecutive men at public health centers...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Oxford University Press
2017-09-01
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| Series: | Sexual Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2050116117300429 |
| _version_ | 1797706466313895936 |
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| author | Yung-Jui Huang, PhD Bang-Ping Jiann, MD |
| author_facet | Yung-Jui Huang, PhD Bang-Ping Jiann, MD |
| author_sort | Yung-Jui Huang, PhD |
| collection | DOAJ |
| description | Introduction: Areca nut chewing has been shown to increase the risk of cardiovascular disease, but its association with erectile dysfunction (ED) has not been investigated.
Aim: To investigate the association between areca nut chewing and risk of ED.
Methods: Consecutive men at public health centers for oral malignancy screening or health checkup were invited to complete a questionnaire.
Main Outcome Measure: The Sexual Health Inventory for Men (SHIM).
Results: Of the 2,652 respondents, 1,038 (mean age = 43.8 ± 11.1 years) were eligible for the areca nut chewing group and 1,090 non-areca nut chewers were selected as the age-matched control group. In the areca nut group, the mean duration of chewing was 13.2 ± 9.6 years, 61.7% consumed more than 10 portions per day, and 76.2% used it with betel leaf, 16.7% used it with betel inflorescence, and 7.1% used it with betel leaf and inflorescence. Smoking, alcohol drinking, obesity, hypertension, and diabetes were more predominant in areca nut chewers compared with controls. ED defined by self-report and by SHIM score was more prevalent in areca nut chewers than in controls (13.7% vs 9.8% and 48.7% vs 43.3%, respectively; P < .05 for the two comparisons). Areca nut use with betel inflorescence was associated with a higher risk of ED (odds ratio = 2.25, 95% confidence interval = 1.55–3.28) with a dose-dependent effect, whereas using it with betel leaf was not (odds ratio = 1.00, 95% confidence interval = 0.79–1.26) after adjustment of possible confounders.
Conclusion: Areca nut chewing with betel inflorescence was associated with an increased risk of ED. These findings warrant further studies.
Huang Y-J, Jiann B-P. Association of Areca Nut Chewing With Risk of Erectile Dysfunction. Sex Med 2017;5:e163–e168. |
| first_indexed | 2024-03-12T05:52:40Z |
| format | Article |
| id | doaj.art-8b9d8f844bc34d4fb2f7bbb66cfda87a |
| institution | Directory Open Access Journal |
| issn | 2050-1161 |
| language | English |
| last_indexed | 2024-03-12T05:52:40Z |
| publishDate | 2017-09-01 |
| publisher | Oxford University Press |
| record_format | Article |
| series | Sexual Medicine |
| spelling | doaj.art-8b9d8f844bc34d4fb2f7bbb66cfda87a2023-09-03T05:01:31ZengOxford University PressSexual Medicine2050-11612017-09-0153e163e16810.1016/j.esxm.2017.05.002Association of Areca Nut Chewing With Risk of Erectile DysfunctionYung-Jui Huang, PhD0Bang-Ping Jiann, MD1Department of Surgery, Kaohsiung Veterans General Hospital and Graduate School of Human Sexuality, Shu-Te University, Kaohsiung, TaiwanDepartment of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung and School of Medicine, National Yang-Ming University, Taipei, TaiwanIntroduction: Areca nut chewing has been shown to increase the risk of cardiovascular disease, but its association with erectile dysfunction (ED) has not been investigated. Aim: To investigate the association between areca nut chewing and risk of ED. Methods: Consecutive men at public health centers for oral malignancy screening or health checkup were invited to complete a questionnaire. Main Outcome Measure: The Sexual Health Inventory for Men (SHIM). Results: Of the 2,652 respondents, 1,038 (mean age = 43.8 ± 11.1 years) were eligible for the areca nut chewing group and 1,090 non-areca nut chewers were selected as the age-matched control group. In the areca nut group, the mean duration of chewing was 13.2 ± 9.6 years, 61.7% consumed more than 10 portions per day, and 76.2% used it with betel leaf, 16.7% used it with betel inflorescence, and 7.1% used it with betel leaf and inflorescence. Smoking, alcohol drinking, obesity, hypertension, and diabetes were more predominant in areca nut chewers compared with controls. ED defined by self-report and by SHIM score was more prevalent in areca nut chewers than in controls (13.7% vs 9.8% and 48.7% vs 43.3%, respectively; P < .05 for the two comparisons). Areca nut use with betel inflorescence was associated with a higher risk of ED (odds ratio = 2.25, 95% confidence interval = 1.55–3.28) with a dose-dependent effect, whereas using it with betel leaf was not (odds ratio = 1.00, 95% confidence interval = 0.79–1.26) after adjustment of possible confounders. Conclusion: Areca nut chewing with betel inflorescence was associated with an increased risk of ED. These findings warrant further studies. Huang Y-J, Jiann B-P. Association of Areca Nut Chewing With Risk of Erectile Dysfunction. Sex Med 2017;5:e163–e168.http://www.sciencedirect.com/science/article/pii/S2050116117300429Areca NutBetel InflorescenceErectile DysfunctionPsychoactive Substance |
| spellingShingle | Yung-Jui Huang, PhD Bang-Ping Jiann, MD Association of Areca Nut Chewing With Risk of Erectile Dysfunction Sexual Medicine Areca Nut Betel Inflorescence Erectile Dysfunction Psychoactive Substance |
| title | Association of Areca Nut Chewing With Risk of Erectile Dysfunction |
| title_full | Association of Areca Nut Chewing With Risk of Erectile Dysfunction |
| title_fullStr | Association of Areca Nut Chewing With Risk of Erectile Dysfunction |
| title_full_unstemmed | Association of Areca Nut Chewing With Risk of Erectile Dysfunction |
| title_short | Association of Areca Nut Chewing With Risk of Erectile Dysfunction |
| title_sort | association of areca nut chewing with risk of erectile dysfunction |
| topic | Areca Nut Betel Inflorescence Erectile Dysfunction Psychoactive Substance |
| url | http://www.sciencedirect.com/science/article/pii/S2050116117300429 |
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