Design, automated synthesis and immunological evaluation of NOD2-ligand–antigen conjugates
The covalent attachment of an innate immune system stimulating agent to an antigen can provide active vaccine modalities capable of eliciting a potent immune response against the incorporated antigen. Here we describe the design, automated synthesis and immunological evaluation of a set of four mura...
Main Authors: | Marian M. J. H. P. Willems, Gijs G. Zom, Nico Meeuwenoord, Ferry A. Ossendorp, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2014-06-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.10.148 |
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