Activity-regulated cytoskeletal-associated protein (Arc) in presynaptic terminals and extracellular vesicles in hippocampal synapses

Activity-regulated cytoskeletal-associated protein (Arc) in presynaptic terminals and extracellular vesicles in hippocampal synapses

The activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) is a neuron-specific immediate early gene (IEG) product. The protein regulates synaptic strength through modulation of spine density and morphology, AMPA receptor endocytosis, and as being part of a retrovirus-like inter-cellular co...

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Bibliographic Details
Main Authors: Håvard Ringsevjen, Daniel Lawer Egbenya, Malte Bieler, Svend Davanger, Suleman Hussain
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Arc
hippocampus
synapse
extracellular vesicles
electron microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1225533/full

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