Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change?
ABSTRACTThe emergence and evolutionary path of Candida auris poses an intriguing scientific enigma. Its isolation from a pet dog’s oral cavity in Kansas, reported by White et al. (T. C. White, B. D. Esquivel, E. M. Rouse Salcido, A. M. Schweiker, et al., mBio 15:e03080-23, 2024, https://doi.org/10.1...
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| Format: | Article |
| Language: | English |
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American Society for Microbiology
2024-04-01
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| Series: | mBio |
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| Online Access: | https://journals.asm.org/doi/10.1128/mbio.00146-24 |
| _version_ | 1797215298911207424 |
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| author | Victor Garcia-Bustos |
| author_facet | Victor Garcia-Bustos |
| author_sort | Victor Garcia-Bustos |
| collection | DOAJ |
| description | ABSTRACTThe emergence and evolutionary path of Candida auris poses an intriguing scientific enigma. Its isolation from a pet dog’s oral cavity in Kansas, reported by White et al. (T. C. White, B. D. Esquivel, E. M. Rouse Salcido, A. M. Schweiker, et al., mBio 15:e03080-23, 2024, https://doi.org/10.1128/mbio.03080-23), carries significant implications. This discovery intensifies concerns about its hypothetical capacity for zoonotic transmission, particularly considering the dog’s extensive human contact and the absence of secondary animal/human cases in both animals and humans. The findings challenge established notions of C. auris transmissibility and underscore the need for further investigation into the transmission dynamics, especially zooanthroponotic pathways. It raises concerns about its adaptability in different hosts and environments, highlighting potential role of environmental and animal reservoirs in its dissemination. Critical points include the evolving thermal tolerance and the genetic divergence in the isolate. This case exemplifies the necessity for an integrated One Health approach, combining human, animal, and environmental health perspectives, to unravel the complexities of C. auris’s emergence and behavior. |
| first_indexed | 2024-04-24T11:27:51Z |
| format | Article |
| id | doaj.art-8ba4e3600ea44249b3cd6c71e1272965 |
| institution | Directory Open Access Journal |
| issn | 2150-7511 |
| language | English |
| last_indexed | 2024-04-24T11:27:51Z |
| publishDate | 2024-04-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | mBio |
| spelling | doaj.art-8ba4e3600ea44249b3cd6c71e12729652024-04-10T13:01:15ZengAmerican Society for MicrobiologymBio2150-75112024-04-0115410.1128/mbio.00146-24Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change?Victor Garcia-Bustos0Severe Infection Research Group, Health Research Institute La Fe, Valencia, SpainABSTRACTThe emergence and evolutionary path of Candida auris poses an intriguing scientific enigma. Its isolation from a pet dog’s oral cavity in Kansas, reported by White et al. (T. C. White, B. D. Esquivel, E. M. Rouse Salcido, A. M. Schweiker, et al., mBio 15:e03080-23, 2024, https://doi.org/10.1128/mbio.03080-23), carries significant implications. This discovery intensifies concerns about its hypothetical capacity for zoonotic transmission, particularly considering the dog’s extensive human contact and the absence of secondary animal/human cases in both animals and humans. The findings challenge established notions of C. auris transmissibility and underscore the need for further investigation into the transmission dynamics, especially zooanthroponotic pathways. It raises concerns about its adaptability in different hosts and environments, highlighting potential role of environmental and animal reservoirs in its dissemination. Critical points include the evolving thermal tolerance and the genetic divergence in the isolate. This case exemplifies the necessity for an integrated One Health approach, combining human, animal, and environmental health perspectives, to unravel the complexities of C. auris’s emergence and behavior.https://journals.asm.org/doi/10.1128/mbio.00146-24Candida auriszoonosisdoganimalthermal resistanceclimate change |
| spellingShingle | Victor Garcia-Bustos Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change? mBio Candida auris zoonosis dog animal thermal resistance climate change |
| title | Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change? |
| title_full | Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change? |
| title_fullStr | Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change? |
| title_full_unstemmed | Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change? |
| title_short | Is Candida auris the first multidrug-resistant fungal zoonosis emerging from climate change? |
| title_sort | is candida auris the first multidrug resistant fungal zoonosis emerging from climate change |
| topic | Candida auris zoonosis dog animal thermal resistance climate change |
| url | https://journals.asm.org/doi/10.1128/mbio.00146-24 |
| work_keys_str_mv | AT victorgarciabustos iscandidaauristhefirstmultidrugresistantfungalzoonosisemergingfromclimatechange |