Structure–Activity Relationship of PAD4 Inhibitors and Their Role in Tumor Immunotherapy

Structure–Activity Relationship of PAD4 Inhibitors and Their Role in Tumor Immunotherapy

Protein arginine deiminase 4 (PAD4) plays an important role in cancer progression by participating in gene regulation, protein modification, and neutrophil extracellular trap (NET) formation. Many reversible and irreversible PAD4 inhibitors have been reported recently. In this review, we summarize t...

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Bibliographic Details
Main Authors:	Yijiang Jia, Renbo Jia, Ayijiang Taledaohan, Yanming Wang, Yuji Wang
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	Pharmaceutics
Subjects:	review PAD4 PAD4 inhibitor structure–activity relationship antitumor immunity combination therapy strategies
Online Access:	https://www.mdpi.com/1999-4923/16/3/335

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