Heritability of subcortical volumetric traits in mesial temporal lobe epilepsy.

OBJECTIVES: We aimed to 1) determine if subcortical volume deficits are common to mesial temporal lobe epilepsy (MTLE) patients and their unaffected siblings 2) assess the suitability of subcortical volumetric traits as endophenotypes for MTLE. METHODS: MRI-based volume measurements of the hippocamp...

Full description

Bibliographic Details
Main Authors: Saud Alhusaini, Cathy Scanlon, Lisa Ronan, Sinead Maguire, James F Meaney, Andrew J Fagan, Gerard Boyle, Gabor Borgulya, Parameswaran M Iyer, Paul Brennan, Daniel Costello, Elijah Chaila, Mary Fitzsimons, Colin P Doherty, Norman Delanty, Gianpiero L Cavalleri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633933?pdf=render