Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report
Essential thrombocythemia (ET) is a very rare disorder with 1- /100,000 population in the world. The incidence of this abnormality is still obscure in Indonesia. We report a case of ET, women of age 74 years old that came to Sanjiwani Hospital with gum bleeding. This case is confirmed based on WHO c...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa
2018-05-01
|
| Series: | WMJ (Warmadewa Medical Journal) |
| Subjects: | |
| Online Access: | https://www.ejournal.warmadewa.ac.id/index.php/warmadewa_medical_journal/article/view/644/pdf |
| _version_ | 1797650769301733376 |
|---|---|
| author | Ni Wayan Sri Wardani I Ketut Ery Purnama Warsana Putra Ni Made Renny A Rena |
| author_facet | Ni Wayan Sri Wardani I Ketut Ery Purnama Warsana Putra Ni Made Renny A Rena |
| author_sort | Ni Wayan Sri Wardani |
| collection | DOAJ |
| description | Essential thrombocythemia (ET) is a very rare disorder with 1- /100,000 population in the world. The incidence of this abnormality is still obscure in Indonesia. We report a case of ET, women of age 74 years old that came to Sanjiwani Hospital with gum bleeding. This case is confirmed based on WHO criteria of ET which are the increasing of thrombocyte of a number of increase >450 /µL3, proliferation of megakaryocyte cell on bone marrow biopsy, also not meeting any other WHO criteria for also not meeting any other WHO criteria for BCR-ABL1+CML, Polycythemia Vera, Chronic Myeloid Leukemia, Myelodysplastic Syndrome, or other myeloid neoplasm diseases. Management of this case is based on risk adapted treatment algorithm considering three major risk factors for thrombosis (history of thrombosis, JAK2/MPL mutations, and advanced age). This case is categorized as high risk patient for thrombosis, so that treated with antiplatelet aggregation (aspilets) and anagrelide after hydroxyurea clinically unresponsive. |
| first_indexed | 2024-03-11T16:05:13Z |
| format | Article |
| id | doaj.art-8ba6fc2e6cc24b64ba14437b06d057d3 |
| institution | Directory Open Access Journal |
| issn | 2527-4627 2579-9010 |
| language | English |
| last_indexed | 2024-03-11T16:05:13Z |
| publishDate | 2018-05-01 |
| publisher | Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa |
| record_format | Article |
| series | WMJ (Warmadewa Medical Journal) |
| spelling | doaj.art-8ba6fc2e6cc24b64ba14437b06d057d32023-10-25T03:59:33ZengFakultas Kedokteran dan Ilmu Kesehatan, Universitas WarmadewaWMJ (Warmadewa Medical Journal)2527-46272579-90102018-05-01311520https://doi.org/10.22225/wmj.3.1.644.15-20Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case ReportNi Wayan Sri Wardani0I Ketut Ery Purnama Warsana Putra1Ni Made Renny A Rena2RSUD Sanjiwani RSUD SanjiwaniRSUP Sanglah DenpasarEssential thrombocythemia (ET) is a very rare disorder with 1- /100,000 population in the world. The incidence of this abnormality is still obscure in Indonesia. We report a case of ET, women of age 74 years old that came to Sanjiwani Hospital with gum bleeding. This case is confirmed based on WHO criteria of ET which are the increasing of thrombocyte of a number of increase >450 /µL3, proliferation of megakaryocyte cell on bone marrow biopsy, also not meeting any other WHO criteria for also not meeting any other WHO criteria for BCR-ABL1+CML, Polycythemia Vera, Chronic Myeloid Leukemia, Myelodysplastic Syndrome, or other myeloid neoplasm diseases. Management of this case is based on risk adapted treatment algorithm considering three major risk factors for thrombosis (history of thrombosis, JAK2/MPL mutations, and advanced age). This case is categorized as high risk patient for thrombosis, so that treated with antiplatelet aggregation (aspilets) and anagrelide after hydroxyurea clinically unresponsive. https://www.ejournal.warmadewa.ac.id/index.php/warmadewa_medical_journal/article/view/644/pdfessential trombositosishemoragikthrombosis |
| spellingShingle | Ni Wayan Sri Wardani I Ketut Ery Purnama Warsana Putra Ni Made Renny A Rena Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report WMJ (Warmadewa Medical Journal) essential trombositosis hemoragik thrombosis |
| title | Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report |
| title_full | Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report |
| title_fullStr | Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report |
| title_full_unstemmed | Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report |
| title_short | Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report |
| title_sort | diagnosis and management of essential thrombocythemia in sanjiwani hospital gianyar bali a case report |
| topic | essential trombositosis hemoragik thrombosis |
| url | https://www.ejournal.warmadewa.ac.id/index.php/warmadewa_medical_journal/article/view/644/pdf |
| work_keys_str_mv | AT niwayansriwardani diagnosisandmanagementofessentialthrombocythemiainsanjiwanihospitalgianyarbaliacasereport AT iketuterypurnamawarsanaputra diagnosisandmanagementofessentialthrombocythemiainsanjiwanihospitalgianyarbaliacasereport AT nimaderennyarena diagnosisandmanagementofessentialthrombocythemiainsanjiwanihospitalgianyarbaliacasereport |