Ventricular function in Chagas' heart disease

Invasive and noninvasive methods used to evaluate ventricular function in Chagas's disease are reviewed. The traditional indices of overall ventricular performance reflect interaction of preload, contractility, afterload and heart rate. Therefore, they are unable to distinguish changes in contr...

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Main Authors: Benedito Carlos Maciel, Oswaldo César de Almeida Filho, André Schmidt, José Antonio Marin-Neto
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801995000200012&lng=en&tlng=en
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author Benedito Carlos Maciel
Oswaldo César de Almeida Filho
André Schmidt
José Antonio Marin-Neto
author_facet Benedito Carlos Maciel
Oswaldo César de Almeida Filho
André Schmidt
José Antonio Marin-Neto
author_sort Benedito Carlos Maciel
collection DOAJ
description Invasive and noninvasive methods used to evaluate ventricular function in Chagas's disease are reviewed. The traditional indices of overall ventricular performance reflect interaction of preload, contractility, afterload and heart rate. Therefore, they are unable to distinguish changes in contractility from modifications of loading conditions. The role of ventricular function as a predictor of mortality in chronic Chagas' heart disease is discussed. Ventricular function abnormalities in patients with indeterminate and digestive forms of Chagas' disease are especially emphasized. Finally, the evidence of early impairment of diastolic performance in patients with Chagas' disease is presented.
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spelling doaj.art-8ba70da2b328449e9120013a3d93873a2022-12-21T20:08:59ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-9460113281482010.1590/S1516-31801995000200012S1516-31801995000200012Ventricular function in Chagas' heart diseaseBenedito Carlos Maciel0Oswaldo César de Almeida Filho1André Schmidt2José Antonio Marin-Neto3Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloInvasive and noninvasive methods used to evaluate ventricular function in Chagas's disease are reviewed. The traditional indices of overall ventricular performance reflect interaction of preload, contractility, afterload and heart rate. Therefore, they are unable to distinguish changes in contractility from modifications of loading conditions. The role of ventricular function as a predictor of mortality in chronic Chagas' heart disease is discussed. Ventricular function abnormalities in patients with indeterminate and digestive forms of Chagas' disease are especially emphasized. Finally, the evidence of early impairment of diastolic performance in patients with Chagas' disease is presented.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801995000200012&lng=en&tlng=enChagas' diseaseVentricular function
spellingShingle Benedito Carlos Maciel
Oswaldo César de Almeida Filho
André Schmidt
José Antonio Marin-Neto
Ventricular function in Chagas' heart disease
São Paulo Medical Journal
Chagas' disease
Ventricular function
title Ventricular function in Chagas' heart disease
title_full Ventricular function in Chagas' heart disease
title_fullStr Ventricular function in Chagas' heart disease
title_full_unstemmed Ventricular function in Chagas' heart disease
title_short Ventricular function in Chagas' heart disease
title_sort ventricular function in chagas heart disease
topic Chagas' disease
Ventricular function
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801995000200012&lng=en&tlng=en
work_keys_str_mv AT beneditocarlosmaciel ventricularfunctioninchagasheartdisease
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AT andreschmidt ventricularfunctioninchagasheartdisease
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