MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft

Here, MineLoC is described as a pipeline developed to generate 3D printable models of master templates for Lab-on-a-Chip (LoC) by using a popular multi-player sandbox game “Minecraft”. The user can draw a simple diagram describing the channels and chambers of the Lab-on-a-Chip de...

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Main Authors: Kyukwang Kim, Hyeongkeun Kim, Seunggyu Kim, Jessie S. Jeon
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/18/6/1896
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author Kyukwang Kim
Hyeongkeun Kim
Seunggyu Kim
Jessie S. Jeon
author_facet Kyukwang Kim
Hyeongkeun Kim
Seunggyu Kim
Jessie S. Jeon
author_sort Kyukwang Kim
collection DOAJ
description Here, MineLoC is described as a pipeline developed to generate 3D printable models of master templates for Lab-on-a-Chip (LoC) by using a popular multi-player sandbox game “Minecraft”. The user can draw a simple diagram describing the channels and chambers of the Lab-on-a-Chip devices with pre-registered color codes which indicate the height of the generated structure. MineLoC converts the diagram into large chunks of blocks (equal sized cube units composing every object in the game) in the game world. The user and co-workers can simultaneously access the game and edit, modify, or review, which is a feature not generally supported by conventional design software. Once the review is complete, the resultant structure can be exported into a stereolithography (STL) file which can be used in additive manufacturing. Then, the Lab-on-a-Chip device can be fabricated by the standard protocol to produce a Lab-on-a-Chip. The simple polydimethylsiloxane (PDMS) device for the bacterial growth measurement used in the previous research was copied by the proposed method. The error calculation by a 3D model comparison showed an accuracy of 86%. It is anticipated that this work will facilitate more use of 3D printer-based Lab-on-a-Chip fabrication, which greatly lowers the entry barrier in the field of Lab-on-a-Chip research.
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spelling doaj.art-8ba91f96121d468ab5079f2f65c8ed792022-12-22T04:01:05ZengMDPI AGSensors1424-82202018-06-01186189610.3390/s18061896s18061896MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, MinecraftKyukwang Kim0Hyeongkeun Kim1Seunggyu Kim2Jessie S. Jeon3Robotics Program, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, KoreaDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, KoreaDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, KoreaDepartment of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 34141, KoreaHere, MineLoC is described as a pipeline developed to generate 3D printable models of master templates for Lab-on-a-Chip (LoC) by using a popular multi-player sandbox game “Minecraft”. The user can draw a simple diagram describing the channels and chambers of the Lab-on-a-Chip devices with pre-registered color codes which indicate the height of the generated structure. MineLoC converts the diagram into large chunks of blocks (equal sized cube units composing every object in the game) in the game world. The user and co-workers can simultaneously access the game and edit, modify, or review, which is a feature not generally supported by conventional design software. Once the review is complete, the resultant structure can be exported into a stereolithography (STL) file which can be used in additive manufacturing. Then, the Lab-on-a-Chip device can be fabricated by the standard protocol to produce a Lab-on-a-Chip. The simple polydimethylsiloxane (PDMS) device for the bacterial growth measurement used in the previous research was copied by the proposed method. The error calculation by a 3D model comparison showed an accuracy of 86%. It is anticipated that this work will facilitate more use of 3D printer-based Lab-on-a-Chip fabrication, which greatly lowers the entry barrier in the field of Lab-on-a-Chip research.http://www.mdpi.com/1424-8220/18/6/1896Lab-on-a-Chip3D printingadditive manufacturingmicrofluidicssolid modeling
spellingShingle Kyukwang Kim
Hyeongkeun Kim
Seunggyu Kim
Jessie S. Jeon
MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft
Sensors
Lab-on-a-Chip
3D printing
additive manufacturing
microfluidics
solid modeling
title MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft
title_full MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft
title_fullStr MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft
title_full_unstemmed MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft
title_short MineLoC: A Rapid Production of Lab-on-a-Chip Biosensors Using 3D Printer and the Sandbox Game, Minecraft
title_sort mineloc a rapid production of lab on a chip biosensors using 3d printer and the sandbox game minecraft
topic Lab-on-a-Chip
3D printing
additive manufacturing
microfluidics
solid modeling
url http://www.mdpi.com/1424-8220/18/6/1896
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