Assessing the Effects of Opioids on Pathological Memory by a Computational Model

Assessing the Effects of Opioids on Pathological Memory by a Computational Model

Introduction: Opioids hijack learning and memory formation mechanisms of brain and induce a pathological memory in the hippocampus. This effect is mainly mediated by modifications in glutamatergic system. Speaking more precisely, Opioids presence in a synapse inhibits blockage of N-Methyl-D-Aspartat...

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Bibliographic Details
Main Authors: Mehdi Borjkhani, Fariba Bahrami, Mahyar Janahmadi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2018-07-01
Series:Basic and Clinical Neuroscience
Subjects:
Opioids
Memory of addiction
Synaptic plasticity
Long-Term Potentiation (LTP)
Hippocampus
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-1150-1&slc_lang=en&sid=1

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