Microfluidic Organoid Cultures Derived from Pancreatic Cancer Biopsies for Personalized Testing of Chemotherapy and Immunotherapy

Microfluidic Organoid Cultures Derived from Pancreatic Cancer Biopsies for Personalized Testing of Chemotherapy and Immunotherapy

Abstract Patient‐derived cancer organoids (PDOs) hold considerable promise for personalizing therapy selection and improving patient outcomes. However, it is challenging to generate PDOs in sufficient numbers to test therapies in standard culture platforms. This challenge is particularly acute for p...

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Bibliographic Details
Main Authors: Daheui Choi, Alan M. Gonzalez‐Suarez, Mihai G. Dumbrava, Michael Medlyn, Jose M. deHoyos‐Vega, Frank Cichocki, Jeffrey S. Miller, Li Ding, Mojun Zhu, Gulnaz Stybayeva, Alexandre Gaspar‐Maia, Daniel D. Billadeau, Wen Wee Ma, Alexander Revzin
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
chemotherapy
immunotherapy
microfluidic device
pancreatic cancer
patient‐derived organoid
Online Access:https://doi.org/10.1002/advs.202303088

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