Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance

Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance

This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disea...

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Bibliographic Details
Main Authors: Anna V. Bocharova, Kseniya V. Vagaitseva, Oksana A. Makeeva, Andrey V. Marusin, Vadim A. Stepanov
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S235234091730714X
Description
Summary:This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile). Keywords: CLU, Cognitive performance, MoCa, Russian population, Elderly, Alzheimer's disease
ISSN:2352-3409

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