A liquid biopsy signature of circulating exosome-derived mRNAs, miRNAs and lncRNAs predict therapeutic efficacy to neoadjuvant chemotherapy in patients with advanced gastric cancer

A liquid biopsy signature of circulating exosome-derived mRNAs, miRNAs and lncRNAs predict therapeutic efficacy to neoadjuvant chemotherapy in patients with advanced gastric cancer

Abstract At present, there is no validated marker to identify the subpopulation of patients with advanced gastric cancer (AGC) who might benefit from neoadjuvant chemotherapy (NACT). In view of this clinical challenge, the identification of non-invasive biomarkers for efficacy prediction of NACT in...

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Bibliographic Details
Main Authors:	Ting Guo, Xiao-Huan Tang, Xiang-Yu Gao, Yuan Zhou, Bo Jin, Zi-Qian Deng, Ying Hu, Xiao-Fang Xing, Zi-Yu Li, Jia-Fu Ji
Format:	Article
Language:	English
Published:	BMC 2022-12-01
Series:	Molecular Cancer
Subjects:	Exosome Multi-omics characteristics of RNAs Advanced gastric cancer Neoadjuvant chemotherapy Biomarker panel for efficacy prediction
Online Access:	https://doi.org/10.1186/s12943-022-01684-9

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