Clinical and Molecular Features of Anti-CENP-B Autoantibodies

Clinical and Molecular Features of Anti-CENP-B Autoantibodies

Centromeric proteins are the foundation for assembling the kinetochore, a macromolecular complex that is essential for accurate chromosome segregation during mitosis. Anti-centromere antibodies (ACAs) are polyclonal autoantibodies targeting centromeric proteins (CENP-A, CENP-B, CENP-C), predominantl...

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Bibliographic Details
Main Authors: Rahul M. Prasad, Alfonso Bellacosa, Tim J. Yen
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Molecular Pathology
Subjects:
centromere
CENP-B
scleroderma
autoimmunity
cancer
Online Access:https://www.mdpi.com/2673-5261/2/4/24

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