Saporin Toxin Delivered by Engineered Colloidal Nanoparticles Is Strongly Effective against Cancer Cells

Saporin Toxin Delivered by Engineered Colloidal Nanoparticles Is Strongly Effective against Cancer Cells

Ribosome-inactivating proteins, including Saporin toxin, have found application in the search for innovative alternative cancer therapies to conventional chemo- and radiotherapy. Saporin’s main mechanism of action involves the inhibition of cytoplasmic protein synthesis. Its strong theoretical effic...

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Bibliographic Details
Main Authors: Lucia Salvioni, Filippo Testa, Linda Barbieri, Marco Giustra, Jessica Armida Bertolini, Giulia Tomaino, Paolo Tortora, Davide Prosperi, Miriam Colombo
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
ribosome-inactivating proteins (RIPs)
toxins
Saporin
colloidal nanoparticles
cancer therapy
breast cancer
Online Access:https://www.mdpi.com/1999-4923/14/7/1517

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