Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors

Donor organ shortage stimulated an active use of donors with expanded evaluation criteria. The main evaluation method was a histological examination of liver graft biopsy specimens before (time-zero biopsy) and after reperfusion (time-1 biopsy). Severe ischemic and reperfusion injuries among recipie...

Full description

Bibliographic Details
Main Authors: M. Sh. Khubutiya, L. N. Zimina, I. E. Galankina, V. A. Gulyaev, M. S. Novruzbekov, O. D. Olisov, K. M. Magomedov
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2018-06-01
Series:Трансплантология (Москва)
Subjects:
Online Access:https://www.jtransplantologiya.ru/jour/article/view/223
_version_ 1797696913121738752
author M. Sh. Khubutiya
L. N. Zimina
I. E. Galankina
V. A. Gulyaev
M. S. Novruzbekov
O. D. Olisov
K. M. Magomedov
author_facet M. Sh. Khubutiya
L. N. Zimina
I. E. Galankina
V. A. Gulyaev
M. S. Novruzbekov
O. D. Olisov
K. M. Magomedov
author_sort M. Sh. Khubutiya
collection DOAJ
description Donor organ shortage stimulated an active use of donors with expanded evaluation criteria. The main evaluation method was a histological examination of liver graft biopsy specimens before (time-zero biopsy) and after reperfusion (time-1 biopsy). Severe ischemic and reperfusion injuries among recipients who received a liver graft made 20.4% and 16.6% respectively. The study showed no impact of small droplet, medium droplet, or even large droplet steatosis (less than 50%) on graft reperfusion injury.
first_indexed 2024-03-12T03:32:53Z
format Article
id doaj.art-8bb310a850ef4cd095ff3a085e61f73b
institution Directory Open Access Journal
issn 2074-0506
2542-0909
language English
last_indexed 2024-03-12T03:32:53Z
publishDate 2018-06-01
publisher N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
record_format Article
series Трансплантология (Москва)
spelling doaj.art-8bb310a850ef4cd095ff3a085e61f73b2023-09-03T13:24:17ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-06-01102879710.23873/2074-0506-2018-10-2-87-97212Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donorsM. Sh. Khubutiya0L. N. Zimina1I. E. Galankina2V. A. Gulyaev3M. S. Novruzbekov4O. D. Olisov5K. M. Magomedov6ГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМГБУЗ НИИ скорой помощи им. Н.В. Склифосовского ДЗМDonor organ shortage stimulated an active use of donors with expanded evaluation criteria. The main evaluation method was a histological examination of liver graft biopsy specimens before (time-zero biopsy) and after reperfusion (time-1 biopsy). Severe ischemic and reperfusion injuries among recipients who received a liver graft made 20.4% and 16.6% respectively. The study showed no impact of small droplet, medium droplet, or even large droplet steatosis (less than 50%) on graft reperfusion injury.https://www.jtransplantologiya.ru/jour/article/view/223стандартные донорыдоноры с расширенными критериями оценкигистологическая оценка печеночного трансплантатастеатоз
spellingShingle M. Sh. Khubutiya
L. N. Zimina
I. E. Galankina
V. A. Gulyaev
M. S. Novruzbekov
O. D. Olisov
K. M. Magomedov
Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
Трансплантология (Москва)
стандартные доноры
доноры с расширенными критериями оценки
гистологическая оценка печеночного трансплантата
стеатоз
title Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
title_full Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
title_fullStr Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
title_full_unstemmed Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
title_short Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
title_sort morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
topic стандартные доноры
доноры с расширенными критериями оценки
гистологическая оценка печеночного трансплантата
стеатоз
url https://www.jtransplantologiya.ru/jour/article/view/223
work_keys_str_mv AT mshkhubutiya morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors
AT lnzimina morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors
AT iegalankina morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors
AT vagulyaev morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors
AT msnovruzbekov morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors
AT odolisov morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors
AT kmmagomedov morphofunctionalevaluationoflivergraftsobtainedfromstandarddonorsandexpandedcriteriadonors