Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs

Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs

Synthetic cannabinoid receptor agonists (SCRAs) continue to make up a significant portion new psychoactive substances (NPS) detected and seized worldwide. Due to their often potent activation of central cannabinoid receptors in vivo, use of SCRAs can result in severe intoxication, in addition to oth...

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Bibliographic Details
Main Authors: Eric Sparkes, Rochelle Boyd, Shuli Chen, Jack W. Markham, Jia Lin Luo, Tahira Foyzun, Humayra Zaman, Charlotte Fletcher, Ross Ellison, Iain S. McGregor, Marina J. Santiago, Felcia Lai, Roy R. Gerona, Mark Connor, David E. Hibbs, Elizabeth A. Cairns, Michelle Glass, Adam Ametovski, Samuel D. Banister
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Psychiatry
Subjects:
synthetic cannabinoid
cannabinoid receptor 1 agonists
pharmacology
cannabinoids
SCRAs
docking
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1010501/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1010501/full

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