Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium

Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium

The HIF prolyl 4-hydroxylases (HIF-P4H) control hypoxia-inducible factor (HIF), a powerful mechanism regulating cellular adaptation to decreased oxygenation. The gastrointestinal epithelium subsists in “physiological hypoxia” and should therefore have an especially well-designed control over this ad...

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Bibliographic Details
Main Authors: Franziska Dengler, Sofia Sova, Antti M. Salo, Joni M. Mäki, Peppi Koivunen, Johanna Myllyharju
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
jejunum
colon
caecum
epithelium
ddPCR
HIF
Online Access:https://www.mdpi.com/1422-0067/22/8/4038

Internet

https://www.mdpi.com/1422-0067/22/8/4038

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