Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells

Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells

Abstract Protein-modifying enzymes regulate the dynamics of myriad post-translational modification (PTM) substrates. Precise characterization of enzyme-substrate associations is essential for the molecular basis of cellular function and phenotype. Methods for direct capturing global substrates of pr...

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Bibliographic Details
Main Authors: Hao Hu, Wei Hu, An-Di Guo, Linhui Zhai, Song Ma, Hui-Jun Nie, Bin-Shan Zhou, Tianxian Liu, Xinglong Jia, Xing Liu, Xuebiao Yao, Minjia Tan, Xiao-Hua Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45765-3

Internet

https://doi.org/10.1038/s41467-024-45765-3

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