Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends
Background: Epidemiology of male reproductive cancers (MRC) is relatively well studied in developed world nations, but little is known about Central Asian states. We aimed to analyze the changing trends for incidence, mortality and 5-year survival MRC across provinces of the Republic of Kazakhstan....
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-08-01
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| Series: | Iranian Journal of Public Health |
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| Online Access: | https://ijph.tums.ac.ir/index.php/ijph/article/view/23498 |
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| author | Khussan Talipbayevich Umurzakov Gulnar Metallovna Shalgumbayeva Dilyara Radikovna Kaydarova Yerbol Smail Askar Ibrayev Sayan Oralchanovich Sagidullin Yuliya Mikhailovna Semenova |
| author_facet | Khussan Talipbayevich Umurzakov Gulnar Metallovna Shalgumbayeva Dilyara Radikovna Kaydarova Yerbol Smail Askar Ibrayev Sayan Oralchanovich Sagidullin Yuliya Mikhailovna Semenova |
| author_sort | Khussan Talipbayevich Umurzakov |
| collection | DOAJ |
| description |
Background: Epidemiology of male reproductive cancers (MRC) is relatively well studied in developed world nations, but little is known about Central Asian states. We aimed to analyze the changing trends for incidence, mortality and 5-year survival MRC across provinces of the Republic of Kazakhstan.
Methods: This was a retrospective cohort study based on data obtained from the Kazakhstan Cancer Registry, which serves as a nationwide database for all histologically confirmed cancer cases. From this, information on all male patients with prostate (PCa) and testicular cancers (TCa) was retrieved for the period from 2010 to 2019. The statistical analysis of official data on incidence, survival, and mortality rates was performed for both the whole country and its provinces.
Results: There was a substantial instability of PCa incidence rates, attributed to the execution of screening program from 2013 to 2017. Still, there was a lack of variations in TCa incidence rates. However, PCa screening program had no influence on reduction of mortality rates, which remained relatively stable. There is much heterogeneity between country’s provinces in incidence and mortality rates. TCa patients were younger than PCa patients and had better 5-year survival.
Conclusion: As compared with many other countries, Kazakhstani men with PCa and TCa have poorer five-year survival, which requires further investigation. Moreover, a careful analysis of diagnostic and treatment strategies utilized at different hospitals across the country would be highly desirable.
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| first_indexed | 2024-04-14T01:57:15Z |
| format | Article |
| id | doaj.art-8bb97bc033384a46949df23e0c232d3b |
| institution | Directory Open Access Journal |
| issn | 2251-6085 2251-6093 |
| language | English |
| last_indexed | 2024-04-14T01:57:15Z |
| publishDate | 2022-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-8bb97bc033384a46949df23e0c232d3b2022-12-22T02:18:59ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932022-08-0151810.18502/ijph.v51i8.10265Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year TrendsKhussan Talipbayevich Umurzakov0Gulnar Metallovna Shalgumbayeva1Dilyara Radikovna Kaydarova2Yerbol Smail3Askar Ibrayev4Sayan Oralchanovich Sagidullin5Yuliya Mikhailovna Semenova6Kazakh institute of Oncology and Radiology, Almaty, KazakhstanSemey Medical University, Semey, KazakhstanKazakh institute of Oncology and Radiology, Almaty, KazakhstanSemey Medical University, Semey, Kazakhstan“Center of Oncology and Surgery”, Oskemen, Kazakhstan“Center of Oncology and Surgery”, Oskemen, KazakhstanSchool of Medicine, Nazarbayev University, Nur-Sultan, Kazakhstan Background: Epidemiology of male reproductive cancers (MRC) is relatively well studied in developed world nations, but little is known about Central Asian states. We aimed to analyze the changing trends for incidence, mortality and 5-year survival MRC across provinces of the Republic of Kazakhstan. Methods: This was a retrospective cohort study based on data obtained from the Kazakhstan Cancer Registry, which serves as a nationwide database for all histologically confirmed cancer cases. From this, information on all male patients with prostate (PCa) and testicular cancers (TCa) was retrieved for the period from 2010 to 2019. The statistical analysis of official data on incidence, survival, and mortality rates was performed for both the whole country and its provinces. Results: There was a substantial instability of PCa incidence rates, attributed to the execution of screening program from 2013 to 2017. Still, there was a lack of variations in TCa incidence rates. However, PCa screening program had no influence on reduction of mortality rates, which remained relatively stable. There is much heterogeneity between country’s provinces in incidence and mortality rates. TCa patients were younger than PCa patients and had better 5-year survival. Conclusion: As compared with many other countries, Kazakhstani men with PCa and TCa have poorer five-year survival, which requires further investigation. Moreover, a careful analysis of diagnostic and treatment strategies utilized at different hospitals across the country would be highly desirable. https://ijph.tums.ac.ir/index.php/ijph/article/view/23498Prostate cancerTesticular cancerIncidenceMortality5-year survival |
| spellingShingle | Khussan Talipbayevich Umurzakov Gulnar Metallovna Shalgumbayeva Dilyara Radikovna Kaydarova Yerbol Smail Askar Ibrayev Sayan Oralchanovich Sagidullin Yuliya Mikhailovna Semenova Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends Iranian Journal of Public Health Prostate cancer Testicular cancer Incidence Mortality 5-year survival |
| title | Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends |
| title_full | Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends |
| title_fullStr | Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends |
| title_full_unstemmed | Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends |
| title_short | Epidemiological Characteristics of Male Reproductive Cancers in the Republic of Kazakhstan: Ten-Year Trends |
| title_sort | epidemiological characteristics of male reproductive cancers in the republic of kazakhstan ten year trends |
| topic | Prostate cancer Testicular cancer Incidence Mortality 5-year survival |
| url | https://ijph.tums.ac.ir/index.php/ijph/article/view/23498 |
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