Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study

Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study

<p>Abstract</p> <p>Background</p> <p>Mechanical ventilation augments lung inflammation resulting from exposure to microbial products. The objective of this study was to test the hypothesis that ventilator-associated immune modulation requires MyD88-dependent signaling....

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Bibliographic Details
Main Authors: Frevert Charles W, Liles W Conrad, Chun Carrie D, Glenny Robb W, Altemeier William A
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Pulmonary Medicine
Online Access:http://www.biomedcentral.com/1471-2466/10/57

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