Carrageenan-Based Compounds as Wound Healing Materials

The following review is focused on carrageenan, a heteroglycan-based substance that is a very significant wound healing biomaterial. Every biomaterial has advantages and weaknesses of its own, but these drawbacks are typically outweighed by combining the material in various ways with other substance...

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Main Authors: Bogdan Neamtu, Andreea Barbu, Mihai Octavian Negrea, Cristian Ștefan Berghea-Neamțu, Dragoș Popescu, Marius Zăhan, Vioara Mireșan
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/16/9117
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author Bogdan Neamtu
Andreea Barbu
Mihai Octavian Negrea
Cristian Ștefan Berghea-Neamțu
Dragoș Popescu
Marius Zăhan
Vioara Mireșan
author_facet Bogdan Neamtu
Andreea Barbu
Mihai Octavian Negrea
Cristian Ștefan Berghea-Neamțu
Dragoș Popescu
Marius Zăhan
Vioara Mireșan
author_sort Bogdan Neamtu
collection DOAJ
description The following review is focused on carrageenan, a heteroglycan-based substance that is a very significant wound healing biomaterial. Every biomaterial has advantages and weaknesses of its own, but these drawbacks are typically outweighed by combining the material in various ways with other substances. Carrageenans’ key benefits include their water solubility, which enables them to keep the wound and periwound damp and absorb the wound exudate. They have low cytotoxicity, antimicrobial and antioxidant qualities, do not stick to the wound bed, and hence do not cause pain when removed from the wounded region. When combined with other materials, they can aid in hemostasis. This review emphasizes the advantages of using carrageenan for wound healing, including the use of several mixes that improve its properties.
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spelling doaj.art-8bbce4b36eae484ba135c15a21850eea2023-11-30T21:34:19ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-08-012316911710.3390/ijms23169117Carrageenan-Based Compounds as Wound Healing MaterialsBogdan Neamtu0Andreea Barbu1Mihai Octavian Negrea2Cristian Ștefan Berghea-Neamțu3Dragoș Popescu4Marius Zăhan5Vioara Mireșan6Pediatric Research Department, Pediatric Hospital Sibiu, 550166 Sibiu, RomaniaPediatric Research Department, Pediatric Hospital Sibiu, 550166 Sibiu, RomaniaFaculty of Medicine, “Lucian Blaga” University of Sibiu, 550169 Sibiu, RomaniaFaculty of Medicine, “Lucian Blaga” University of Sibiu, 550169 Sibiu, RomaniaFaculty of Medicine, “Lucian Blaga” University of Sibiu, 550169 Sibiu, RomaniaFaculty of Animal Science and Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, RomaniaFaculty of Animal Science and Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, RomaniaThe following review is focused on carrageenan, a heteroglycan-based substance that is a very significant wound healing biomaterial. Every biomaterial has advantages and weaknesses of its own, but these drawbacks are typically outweighed by combining the material in various ways with other substances. Carrageenans’ key benefits include their water solubility, which enables them to keep the wound and periwound damp and absorb the wound exudate. They have low cytotoxicity, antimicrobial and antioxidant qualities, do not stick to the wound bed, and hence do not cause pain when removed from the wounded region. When combined with other materials, they can aid in hemostasis. This review emphasizes the advantages of using carrageenan for wound healing, including the use of several mixes that improve its properties.https://www.mdpi.com/1422-0067/23/16/9117carrageenanheteroglycanwound healingbiomaterialinfection controlnanofibers
spellingShingle Bogdan Neamtu
Andreea Barbu
Mihai Octavian Negrea
Cristian Ștefan Berghea-Neamțu
Dragoș Popescu
Marius Zăhan
Vioara Mireșan
Carrageenan-Based Compounds as Wound Healing Materials
International Journal of Molecular Sciences
carrageenan
heteroglycan
wound healing
biomaterial
infection control
nanofibers
title Carrageenan-Based Compounds as Wound Healing Materials
title_full Carrageenan-Based Compounds as Wound Healing Materials
title_fullStr Carrageenan-Based Compounds as Wound Healing Materials
title_full_unstemmed Carrageenan-Based Compounds as Wound Healing Materials
title_short Carrageenan-Based Compounds as Wound Healing Materials
title_sort carrageenan based compounds as wound healing materials
topic carrageenan
heteroglycan
wound healing
biomaterial
infection control
nanofibers
url https://www.mdpi.com/1422-0067/23/16/9117
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AT cristianstefanbergheaneamtu carrageenanbasedcompoundsaswoundhealingmaterials
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