Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways

Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways

<p>Abstract</p> <p>Background</p> <p>In peripheral airways, acetylcholine induces contraction via activation of muscarinic M2-and M3-receptor subtypes (M<sub>2</sub>R and M<sub>3</sub>R). Cholinergic hypersensitivity is associated with chronic ob...

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Bibliographic Details
Main Authors: Kummer Wolfgang, Wiegand Silke, Banno Yoshiko, Schütz Werner, Akinci Sibel, Powaga Norbert, Pfaff Melanie, Wess Jürgen, Haberberger Rainer
Format: Article
Language:English
Published: BMC 2005-05-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/6/1/48

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