Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats
The present study was undertaken to assess the analgesic effect of red and white lotus (Nelumbo nucifera) seeds in albino rats. The analgesic action in acute pain model was studied by tail flick method. The methanolic extracts of lotus seeds were screened for&...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Veterinary World
2009-01-01
|
| Series: | Veterinary World |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=36517 |
| _version_ | 1818590668609552384 |
|---|---|
| author | P. Vikrama Chakravarthi N. Gopakumar |
| author_facet | P. Vikrama Chakravarthi N. Gopakumar |
| author_sort | P. Vikrama Chakravarthi |
| collection | DOAJ |
| description | The present study was undertaken to assess the analgesic effect of red and white lotus (Nelumbo nucifera) seeds in albino rats. The analgesic action in acute pain model was studied by tail flick method. The methanolic extracts of lotus seeds were screened for phytochemical analysis and it’s revealed the presence of all components excluding tannins. The Forty eight adult Sprague-Dawley rats were divided into six groups of eight each and maintained under ideal laboratory conditions. Group I was taken as control and group II treated with the standard drug diclofenac potassium @ 3mg/kg on 7thday of study. The methanolic extract of Nelumbo nucifera seeds of red and white varieties @ 400mg/kg and 600mg/kg were fed to group III, IV, V and VI respectively, for 7 days.  It is observed that the both lotus seed extracts shows considerable analgesic effect in acute pain model which is less than the effect of Diclofenac group. The higher dose groups of lotus seed extracts (600mg/kg) were revealed more activity than their corresponding lower dose. While evaluating all groups, the higher dose group of white lotus seed (600mg/kg), exhibited more pronounced activity than other extracts. [Vet World 2009; 2(9.000): 355-357] |
| first_indexed | 2024-12-16T10:00:12Z |
| format | Article |
| id | doaj.art-8bbf77bb3d9c40afa73f28b99732accb |
| institution | Directory Open Access Journal |
| issn | 0972-8988 2231-0916 |
| language | English |
| last_indexed | 2024-12-16T10:00:12Z |
| publishDate | 2009-01-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj.art-8bbf77bb3d9c40afa73f28b99732accb2022-12-21T22:35:48ZengVeterinary WorldVeterinary World0972-89882231-09162009-01-0129.000355357Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino ratsP. Vikrama ChakravarthiN. GopakumarThe present study was undertaken to assess the analgesic effect of red and white lotus (Nelumbo nucifera) seeds in albino rats. The analgesic action in acute pain model was studied by tail flick method. The methanolic extracts of lotus seeds were screened for phytochemical analysis and it’s revealed the presence of all components excluding tannins. The Forty eight adult Sprague-Dawley rats were divided into six groups of eight each and maintained under ideal laboratory conditions. Group I was taken as control and group II treated with the standard drug diclofenac potassium @ 3mg/kg on 7thday of study. The methanolic extract of Nelumbo nucifera seeds of red and white varieties @ 400mg/kg and 600mg/kg were fed to group III, IV, V and VI respectively, for 7 days.  It is observed that the both lotus seed extracts shows considerable analgesic effect in acute pain model which is less than the effect of Diclofenac group. The higher dose groups of lotus seed extracts (600mg/kg) were revealed more activity than their corresponding lower dose. While evaluating all groups, the higher dose group of white lotus seed (600mg/kg), exhibited more pronounced activity than other extracts. [Vet World 2009; 2(9.000): 355-357]http://www.scopemed.org/fulltextpdf.php?mno=36517Analgesic activityLotus seedsTail Flick methodPain |
| spellingShingle | P. Vikrama Chakravarthi N. Gopakumar Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats Veterinary World Analgesic activity Lotus seeds Tail Flick method Pain |
| title | Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats |
| title_full | Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats |
| title_fullStr | Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats |
| title_full_unstemmed | Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats |
| title_short | Evaluation of analgesic activity of lotus seeds (Nelumbo nucifera) in albino rats |
| title_sort | evaluation of analgesic activity of lotus seeds nelumbo nucifera in albino rats |
| topic | Analgesic activity Lotus seeds Tail Flick method Pain |
| url | http://www.scopemed.org/fulltextpdf.php?mno=36517 |
| work_keys_str_mv | AT pvikramachakravarthi evaluationofanalgesicactivityoflotusseedsnelumbonuciferainalbinorats AT ngopakumar evaluationofanalgesicactivityoflotusseedsnelumbonuciferainalbinorats |