Abnormal levels of expression of microRNAs in peripheral blood of patients with traumatic brain injury are induced by microglial activation and correlated with severity of injury

Abnormal levels of expression of microRNAs in peripheral blood of patients with traumatic brain injury are induced by microglial activation and correlated with severity of injury

Abstract Background Microglia play a crucial role in regulating the progression of traumatic brain injury (TBI). In specific, microglia can self-activate and secrete various substances that exacerbate or alleviate the neuroimmune response to TBI. In addition, microRNAs (miRNAs) are involved in the f...

Full description

Bibliographic Details
Main Authors: Shuo Feng, Zhangying Wu, Xianping Zheng, Zhiwei Shao, Qiang Lin, Shoutian Sun
Format: Article
Language:English
Published: BMC 2024-03-01
Series:European Journal of Medical Research
Subjects:
Traumatic brain injury
miRNAs
Microglia
Glasgow Coma Scale
Biomarker
ROC curve
Online Access:https://doi.org/10.1186/s40001-024-01790-y

Internet

https://doi.org/10.1186/s40001-024-01790-y

Similar Items