Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments

Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments

The cell nucleus contains a number of membrane-less organelles or intra-nuclear compartments. These compartments are dynamic structures representing liquid-droplet phases which are only slightly denser than the bulk intra-nuclear fluid. They possess different functions, have diverse morphologies, an...

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Bibliographic Details
Main Authors: Fanchi Meng, Insung Na, Lukasz Kurgan, Vladimir N. Uversky
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
intrinsically disordered protein
cell nucleus
membrane-less organelles
intra-nuclear compartments
DNA-binding protein
RNA-binding protein
Online Access:http://www.mdpi.com/1422-0067/17/1/24

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