Glycyrol Alleviates Acute Kidney Injury by Inhibiting Ferroptsis

Glycyrol Alleviates Acute Kidney Injury by Inhibiting Ferroptsis

Acute kidney injury (AKI) is a common clinical problem with high morbidity and mortality. The discovery of ferroptosis has provided novel insights into the mechanisms underlying AKI and paves the way for developing ferroptosis-based approaches to treat AKI. Glycyrol (GC) is a representative coumarin...

Full description

Bibliographic Details
Main Authors:	Lixing Cao, Kai Han, Lihong Fan, Chong Zhao, Shutao Yin, Hongbo Hu
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	International Journal of Molecular Sciences
Subjects:	glycyrol ferroptosis acute kidney injury HO-1
Online Access:	https://www.mdpi.com/1422-0067/25/5/2458

Similar Items

Glycyrol Alone or in Combination with Gefitinib Is Effective against Gefitinib-Resistant HCC827GR Lung Cancer Cells
by: Shuang Zhao, et al.
Published: (2021-11-01)

Glycyrol attenuates colon injury via promotion of SQSTM1/p62 ubiquitination and autophagy by inhibiting the ubiquitin-specific protease USP8
by: Shangyun Lu, et al.
Published: (2023-04-01)

Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from <i>Glycyrrhiza uralensis</i>
by: Geum Seok Jeong, et al.
Published: (2020-08-01)

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
by: Hongyan Zan, et al.
Published: (2024-12-01)

Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway
by: Minling Pan, et al.
Published: (2023-10-01)

Liproxstatin-1 Alleviated Ischemia/Reperfusion-Induced Acute Kidney Injury via Inhibiting Ferroptosis
by: Zhiyuan Shi, et al.
Published: (2024-01-01)

<i>Myo</i>-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis
by: Huiyue Qi, et al.
Published: (2022-12-01)

Dioscin Protects against Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling
by: Shuang Wang, et al.
Published: (2022-12-01)

<i>Nlrp3</i> Deficiency Alleviates Lipopolysaccharide-Induced Acute Kidney Injury via Suppressing Renal Inflammation and Ferroptosis in Mice
by: Zhilan Li, et al.
Published: (2023-08-01)

Ferrostatin-1 facilitated neurological functional rehabilitation of spinal cord injury mice by inhibiting ferroptosis
by: Zhenhai Zhou, et al.
Published: (2023-09-01)

The Role of Ferroptosis in Acute Kidney Injury
by: Jinshi Zhang, et al.
Published: (2022-06-01)

Loganin Attenuates the Severity of Acute Kidney Injury Induced by Cisplatin through the Inhibition of ERK Activation in Mice
by: Dong-Uk Kim, et al.
Published: (2021-01-01)

Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway
by: Lei Chen, et al.
Published: (2023-04-01)

Sulfide:quinone oxidoreductase alleviates ferroptosis in acute kidney injury via ameliorating mitochondrial dysfunction of renal tubular epithelial cells
by: Fangfang Cai, et al.
Published: (2024-02-01)

Therapeutic potential of dihydroartemisinin in mitigating radiation‐induced lung injury: Inhibition of ferroptosis through Nrf2/HO‐1 pathways in mice
by: Xin Ning, et al.
Published: (2024-02-01)

Three New Compounds, Licopyranol A–C, Together with Eighteen Known Compounds Isolated from <i>Glycyrrhiza glabra</i> L. and Their Antitumor Activities
by: Shanshan Wang, et al.
Published: (2022-09-01)

Ferroptosis: A new insight for treatment of acute kidney injury
by: Shiyang Li, et al.
Published: (2022-11-01)

Regulation of Complement Activation by Heme Oxygenase-1 (HO-1) in Kidney Injury
by: Maria G. Detsika, et al.
Published: (2021-01-01)

WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury
by: Zebin Deng, et al.
Published: (2023-09-01)

Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage
by: Kai Lai, et al.
Published: (2023-03-01)

Ferroptosis and Acute Kidney Injury (AKI): Molecular Mechanisms and Therapeutic Potentials
by: Qi Feng, et al.
Published: (2022-04-01)

Molecular Mechanisms of Ferroptosis and Their Involvement in Acute Kidney Injury
by: Liu J, et al.
Published: (2023-11-01)

Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury
by: Qiming Gong, et al.
Published: (2023-10-01)

VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury
by: Yan Li, et al.
Published: (2023-04-01)

Ferroptosis: A new mechanism of traditional Chinese medicine compounds for treating acute kidney injury
by: Yue Shi, et al.
Published: (2023-07-01)

The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury
by: Xinzhou Yan, et al.
Published: (2024-01-01)

Puerarin alleviated oxidative stress and ferroptosis during renal fibrosis induced by ischemia/reperfusion injury via TLR4/Nox4 pathway in rats
by: Jun Jian, et al.
Published: (2023-08-01)

Inhibition of Indoxyl Sulfate-Induced Reactive Oxygen Species-Related Ferroptosis Alleviates Renal Cell Injury In Vitro and Chronic Kidney Disease Progression In Vivo
by: Li-Ting Tsai, et al.
Published: (2023-10-01)

Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling
by: Xueyan Li, et al.
Published: (2024-04-01)

Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis
by: Pengfei Liu, et al.
Published: (2020-02-01)

Up-regulation of GCLM alleviates ferroptosis in renal tubular epithelial cells induced by hypoxia reoxygenation injury
by: GONG Shuiqin, et al.
Published: (2023-04-01)

Autophagy-dependent ferroptosis in kidney disease
by: Yuanting Yang, et al.
Published: (2023-01-01)

SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation
by: Yangtian Yan, et al.
Published: (2024-02-01)

Acacetin alleviates neuroinflammation and oxidative stress injury via the Nrf2/HO-1 pathway in a mouse model of spinal cord injury
by: Zhang Xin, et al.
Published: (2022-12-01)

Aristolochic acid induces acute kidney injury through ferroptosis
by: Xuan Huang, et al.
Published: (2024-03-01)

ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury
by: Yue Wang, et al.
Published: (2022-05-01)

Astaxanthin alleviates PM2.5-induced cardiomyocyte injury via inhibiting ferroptosis
by: Jingyi Ren, et al.
Published: (2023-11-01)

Oxidative Stress and Ischemia/Reperfusion Injury in Kidney Transplantation: Focus on Ferroptosis, Mitophagy and New Antioxidants
by: Simona Granata, et al.
Published: (2022-04-01)

Acute kidney injury: exploring endoplasmic reticulum stress-mediated cell death
by: Cong Cheng, et al.
Published: (2024-02-01)

Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis
by: Ya Lv, et al.
Published: (2023-04-01)