COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation

Abstract Since the onset of the COVID-19 outbreak, numerous articles have highlighted a possible link between COVID-19 vaccination or infection and Herpesviridae co-infection or reactivation. The authors conducted an exhaustive literature review on this topic, the results of which are presented indi...

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Main Authors: Alba Navarro-Bielsa, Tamara Gracia-Cazaña, Beatriz Aldea-Manrique, Isabel Abadías-Granado, Adrián Ballano, Isabel Bernad, Yolanda Gilaberte
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2023-06-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962023000300347&tlng=en
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author Alba Navarro-Bielsa
Tamara Gracia-Cazaña
Beatriz Aldea-Manrique
Isabel Abadías-Granado
Adrián Ballano
Isabel Bernad
Yolanda Gilaberte
author_facet Alba Navarro-Bielsa
Tamara Gracia-Cazaña
Beatriz Aldea-Manrique
Isabel Abadías-Granado
Adrián Ballano
Isabel Bernad
Yolanda Gilaberte
author_sort Alba Navarro-Bielsa
collection DOAJ
description Abstract Since the onset of the COVID-19 outbreak, numerous articles have highlighted a possible link between COVID-19 vaccination or infection and Herpesviridae co-infection or reactivation. The authors conducted an exhaustive literature review on this topic, the results of which are presented individually for each member of the Herpesviridae family: Herpes Simplex Virus (HSV) types-1 (HSV-1) and 2 (HSV-2); Varicella-Zoster Virus (VZV); Epstein-Barr Virus (EBV); Cytomegalovirus (CMV); HHV-6; HHV-7; and HHV-8. These human herpesviruses can serve as prognostic markers for the COVID-19 infection and may even underlie some of the clinical manifestations initially attributed to SARS-CoV-2. In addition to SARS-CoV-2 infection, all corresponding vaccines approved to date in Europe appear capable of inducing herpesvirus reactivation. It is important to consider all viruses of the Herpesviridae family when managing patients infected with or recently vaccinated against COVID-19.
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spelling doaj.art-8bca038ab9db487f8015a5bef1e5882c2023-06-30T10:50:00ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962023-06-0198334735410.1016/j.abd.2022.09.004COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivationAlba Navarro-Bielsahttps://orcid.org/0000-0003-1171-6007Tamara Gracia-Cazañahttps://orcid.org/0000-0002-0523-2076Beatriz Aldea-Manriquehttps://orcid.org/0000-0002-2458-0033Isabel Abadías-Granadohttps://orcid.org/0000-0002-5301-1059Adrián Ballanohttps://orcid.org/0000-0001-6256-183XIsabel Bernadhttps://orcid.org/0000-0003-1480-3085Yolanda Gilabertehttps://orcid.org/0000-0001-8034-3617Abstract Since the onset of the COVID-19 outbreak, numerous articles have highlighted a possible link between COVID-19 vaccination or infection and Herpesviridae co-infection or reactivation. The authors conducted an exhaustive literature review on this topic, the results of which are presented individually for each member of the Herpesviridae family: Herpes Simplex Virus (HSV) types-1 (HSV-1) and 2 (HSV-2); Varicella-Zoster Virus (VZV); Epstein-Barr Virus (EBV); Cytomegalovirus (CMV); HHV-6; HHV-7; and HHV-8. These human herpesviruses can serve as prognostic markers for the COVID-19 infection and may even underlie some of the clinical manifestations initially attributed to SARS-CoV-2. In addition to SARS-CoV-2 infection, all corresponding vaccines approved to date in Europe appear capable of inducing herpesvirus reactivation. It is important to consider all viruses of the Herpesviridae family when managing patients infected with or recently vaccinated against COVID-19.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962023000300347&tlng=enCoinfectionCOVID-19Herpesvirus 1, humanHerpesvirus 2, humanLatent infection
spellingShingle Alba Navarro-Bielsa
Tamara Gracia-Cazaña
Beatriz Aldea-Manrique
Isabel Abadías-Granado
Adrián Ballano
Isabel Bernad
Yolanda Gilaberte
COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation
Anais Brasileiros de Dermatologia
Coinfection
COVID-19
Herpesvirus 1, human
Herpesvirus 2, human
Latent infection
title COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation
title_full COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation
title_fullStr COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation
title_full_unstemmed COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation
title_short COVID-19 infection and vaccines: potential triggers of Herpesviridae reactivation
title_sort covid 19 infection and vaccines potential triggers of herpesviridae reactivation
topic Coinfection
COVID-19
Herpesvirus 1, human
Herpesvirus 2, human
Latent infection
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962023000300347&tlng=en
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