Preclinical validation of a new hybrid molecule loaded in liposomes for melanoma management
The aggressiveness of melanoma and lack of effective therapies incite the discovery of novel strategies. Recently, a new dual acting hybrid molecule (HM), combining a triazene and a ʟ-tyrosine analogue, was synthesized. HM was designed to specifically be activated by tyrosinase, the enzyme involved...
Main Authors: | Jacinta O. Pinho, Mariana Matias, Vanda Marques, Carla Eleutério, Célia Fernandes, Lurdes Gano, Joana D. Amaral, Eduarda Mendes, Maria Jesus Perry, João Nuno Moreira, Gert Storm, Ana Paula Francisco, Cecília M.P. Rodrigues, M. Manuela Gaspar |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S075333222201410X |
Similar Items
-
The Challenging Melanoma Landscape: From Early Drug Discovery to Clinical Approval
by: Mariana Matias, et al.
Published: (2021-11-01) -
Response of Skin-Derived and Metastatic Human Malignant Melanoma Cell Lines to Thymoquinone and Thymoquinone-Loaded Liposomes
by: Patrycja Kłos, et al.
Published: (2022-10-01) -
Liposome-Fe3 O4-Doxorubicin Mediated Treatment of Melanoma Tumors
by: Azalia Azlegini, et al.
Published: (2023-03-01) -
pH-Sensitive Liposomes for Enhanced Cellular Uptake and Cytotoxicity of Daunorubicin in Melanoma (B16-BL6) Cell Lines
by: Hamad Alrbyawi, et al.
Published: (2022-05-01) -
Hispolon Cyclodextrin Complexes and Their Inclusion in Liposomes for Enhanced Delivery in Melanoma Cell Lines
by: Ishwor Poudel, et al.
Published: (2022-11-01)