3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight

Plant and animal life forms have progressively developed mechanisms for perceiving and responding to gravity on Earth, where homeostatic mechanisms require feedback. Lack of gravity, as in the International Space Station (ISS), induces acute intra-generational changes in the quality of life. These i...

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Main Authors: Flaminia Aliberti, Elisa Paolin, Laura Benedetti, Gabriella Cusella, Gabriele Ceccarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.937709/full
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author Flaminia Aliberti
Flaminia Aliberti
Elisa Paolin
Elisa Paolin
Laura Benedetti
Gabriella Cusella
Gabriele Ceccarelli
author_facet Flaminia Aliberti
Flaminia Aliberti
Elisa Paolin
Elisa Paolin
Laura Benedetti
Gabriella Cusella
Gabriele Ceccarelli
author_sort Flaminia Aliberti
collection DOAJ
description Plant and animal life forms have progressively developed mechanisms for perceiving and responding to gravity on Earth, where homeostatic mechanisms require feedback. Lack of gravity, as in the International Space Station (ISS), induces acute intra-generational changes in the quality of life. These include reduced bone calcium levels and muscle tone, provoking skin deterioration. All these problems reduce the work efficiency and quality of life of humans not only during exposure to microgravity (µG) but also after returning to Earth. This article discusses forthcoming experiments required under gravity and µG conditions to ensure effective and successful medical treatments for astronauts during long-term space missions, where healthcare is difficult and not guaranteed.
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spelling doaj.art-8bd2630adf6e4b57bb40b44f0db4a7d72022-12-22T02:18:46ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-08-011010.3389/fbioe.2022.9377099377093D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflightFlaminia Aliberti0Flaminia Aliberti1Elisa Paolin2Elisa Paolin3Laura Benedetti4Gabriella Cusella5Gabriele Ceccarelli6Department of Public Health, Experimental and Forensic Medicine, Human Anatomy Unit, University of Pavia, Pavia, ItalyFondazione IRCCS Policlinico San Matteo, Center for Inherited Cardiovascular Diseases, Transplant Research Area, Pavia, ItalyDepartment of Public Health, Experimental and Forensic Medicine, Human Anatomy Unit, University of Pavia, Pavia, ItalyHuman Brain Wave, Turin, ItalyDepartment of Public Health, Experimental and Forensic Medicine, Human Anatomy Unit, University of Pavia, Pavia, ItalyDepartment of Public Health, Experimental and Forensic Medicine, Human Anatomy Unit, University of Pavia, Pavia, ItalyDepartment of Public Health, Experimental and Forensic Medicine, Human Anatomy Unit, University of Pavia, Pavia, ItalyPlant and animal life forms have progressively developed mechanisms for perceiving and responding to gravity on Earth, where homeostatic mechanisms require feedback. Lack of gravity, as in the International Space Station (ISS), induces acute intra-generational changes in the quality of life. These include reduced bone calcium levels and muscle tone, provoking skin deterioration. All these problems reduce the work efficiency and quality of life of humans not only during exposure to microgravity (µG) but also after returning to Earth. This article discusses forthcoming experiments required under gravity and µG conditions to ensure effective and successful medical treatments for astronauts during long-term space missions, where healthcare is difficult and not guaranteed.https://www.frontiersin.org/articles/10.3389/fbioe.2022.937709/fullmicrogravity3D bioprintingmicrograftingskinregenerative medicinewound healing
spellingShingle Flaminia Aliberti
Flaminia Aliberti
Elisa Paolin
Elisa Paolin
Laura Benedetti
Gabriella Cusella
Gabriele Ceccarelli
3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight
Frontiers in Bioengineering and Biotechnology
microgravity
3D bioprinting
micrografting
skin
regenerative medicine
wound healing
title 3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight
title_full 3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight
title_fullStr 3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight
title_full_unstemmed 3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight
title_short 3D bioprinting and Rigenera® micrografting technology: A possible countermeasure for wound healing in spaceflight
title_sort 3d bioprinting and rigenera r micrografting technology a possible countermeasure for wound healing in spaceflight
topic microgravity
3D bioprinting
micrografting
skin
regenerative medicine
wound healing
url https://www.frontiersin.org/articles/10.3389/fbioe.2022.937709/full
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