BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS

Aim. To investigate the levels of fatty aldehydes and oxidised fatty acid radicals in erythrocytes and plasma lipids among patients with atherosclerosis and coronary heart disease (CHD). Material and methods. The study included patients with diagnosed CHD and coronary artery atherosclerosis, as well...

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Main Authors: A. N. Osipenko, N. V. Akulich
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2012-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1204
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author A. N. Osipenko
N. V. Akulich
author_facet A. N. Osipenko
N. V. Akulich
author_sort A. N. Osipenko
collection DOAJ
description Aim. To investigate the levels of fatty aldehydes and oxidised fatty acid radicals in erythrocytes and plasma lipids among patients with atherosclerosis and coronary heart disease (CHD). Material and methods. The study included patients with diagnosed CHD and coronary artery atherosclerosis, as well as healthy volunteers (controls). The levels of fatty aldehydes and oxidised fatty acid radicals were assessed using the capillary gas-liquid chromatography method. Results. CHD patients demonstrated elevated erythrocyte levels of fatty aldehydes and oxidised fatty radicals, as well as an increased relative content of fatty aldehydes in plasma lipids. Conclusion. Blood acidosis could play an important role in the elevation of fatty aldehyde levels in erythrocytes among patients with atherosclerosis and myocardial ischemia.
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spelling doaj.art-8bd51e7986e940d091411765a06808b92023-03-29T21:23:19Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202012-04-010234371007BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSISA. N. Osipenko0N. V. Akulich1УО «Могилевский государственный университет им. А. А. Кулешова», Могилев, БеларусьУО «Могилевский государственный университет им. А. А. Кулешова», Могилев, БеларусьAim. To investigate the levels of fatty aldehydes and oxidised fatty acid radicals in erythrocytes and plasma lipids among patients with atherosclerosis and coronary heart disease (CHD). Material and methods. The study included patients with diagnosed CHD and coronary artery atherosclerosis, as well as healthy volunteers (controls). The levels of fatty aldehydes and oxidised fatty acid radicals were assessed using the capillary gas-liquid chromatography method. Results. CHD patients demonstrated elevated erythrocyte levels of fatty aldehydes and oxidised fatty radicals, as well as an increased relative content of fatty aldehydes in plasma lipids. Conclusion. Blood acidosis could play an important role in the elevation of fatty aldehyde levels in erythrocytes among patients with atherosclerosis and myocardial ischemia.https://russjcardiol.elpub.ru/jour/article/view/1204fatty aldehydesfatty acidsplasmalogen phospholipidsatherosclerosiscoronary heart disease
spellingShingle A. N. Osipenko
N. V. Akulich
BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS
Российский кардиологический журнал
fatty aldehydes
fatty acids
plasmalogen phospholipids
atherosclerosis
coronary heart disease
title BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS
title_full BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS
title_fullStr BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS
title_full_unstemmed BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS
title_short BLOOD LEVELS OF FATTY ALDEHYDES IN CORONARY HEART DISEASE AND ATHEROSCLEROSIS
title_sort blood levels of fatty aldehydes in coronary heart disease and atherosclerosis
topic fatty aldehydes
fatty acids
plasmalogen phospholipids
atherosclerosis
coronary heart disease
url https://russjcardiol.elpub.ru/jour/article/view/1204
work_keys_str_mv AT anosipenko bloodlevelsoffattyaldehydesincoronaryheartdiseaseandatherosclerosis
AT nvakulich bloodlevelsoffattyaldehydesincoronaryheartdiseaseandatherosclerosis