Dynamics of co-substrate pools can constrain and regulate metabolic fluxes

Dynamics of co-substrate pools can constrain and regulate metabolic fluxes

Cycling of co-substrates, whereby a metabolite is converted among alternate forms via different reactions, is ubiquitous in metabolism. Several cycled co-substrates are well known as energy and electron carriers (e.g. ATP and NAD(P)H), but there are also other metabolites that act as cycled co-subst...

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Bibliographic Details
Main Authors: Robert West, Hadrien Delattre, Elad Noor, Elisenda Feliu, Orkun S Soyer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
S. cerevisiae
human
A. thaliana
Online Access:https://elifesciences.org/articles/84379

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