The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis

Auriculotherapy has been extensively used for chronic spontaneous urticaria in China. However, the evidence of its effectiveness and safety for the treatment of chronic spontaneous urticaria is insufficient. Hence, we conducted this study to compare auriculotherapy or auriculotherapy joint treatment...

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Main Authors: Libing Zhu, Yunjin Kim, Zongbao Yang
Format: Article
Language:English
Published: Medical Association of Pharmacopuncture Institute 2018-12-01
Series:Journal of Acupuncture & Meridian Studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2005290118300827
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author Libing Zhu
Yunjin Kim
Zongbao Yang
author_facet Libing Zhu
Yunjin Kim
Zongbao Yang
author_sort Libing Zhu
collection DOAJ
description Auriculotherapy has been extensively used for chronic spontaneous urticaria in China. However, the evidence of its effectiveness and safety for the treatment of chronic spontaneous urticaria is insufficient. Hence, we conducted this study to compare auriculotherapy or auriculotherapy joint treatment with Western medicine for the cure of chronic spontaneous urticaria. This meta-analysis of seven randomized controlled trials showed that auriculotherapy or auriculotherapy joint treatment was significantly superior to Western medicine in curing clinical signs and symptoms of chronic spontaneous urticaria [odds ration (OR), 2.61; 95% confidence interval (CI), 1.54–4.43; p = 0.0004) and also better in total effect rate (OR, 3.81; 95% CI, 2.07–7.01; p<0.0001). But, auriculotherapy or auriculotherapy joint treatment was similar to Western medicine in improving clinical signs and symptoms of chronic spontaneous urticaria (OR, 0.74; 95% CI, 0.35–1.56; p = 0.42). Auriculotherapy or auriculotherapy joint treatment was safer than Western medicine for curing chronic spontaneous urticaria (OR, 0.26; 95% CI, 0.09–0.80; p = 0.02). Auriculotherapy alone or auriculotherapy joint treatment appears to be more effective and safer than Western medicine that contains antihistamines in the treatment of chronic spontaneous urticaria. However, these findings should be interpreted with caution due to the unclear risk bias of methodological quality, and further studies with large-scale, better, and more rigorously designed protocol are necessary to prove these findings. Keywords: auricular acupuncture, auriculotherapy, urticaria, review, meta-analysis
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spelling doaj.art-8bd72e022c964642a0bbf7ad9419d3d92022-12-21T19:57:54ZengMedical Association of Pharmacopuncture InstituteJournal of Acupuncture & Meridian Studies2005-29012018-12-01116343354The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysisLibing Zhu0Yunjin Kim1Zongbao Yang2Department of Medicine, Xiamen University, Xiamen, Fujian, China; Corresponding author. Department of Medicine, Xiamen University, Xiang'an south road, Xiamen, Fujian, China.School of Medicine, Xiamen University Malaysia, Sepang, Selangor, MalaysiaDepartment of Medicine, Xiamen University, Xiamen, Fujian, ChinaAuriculotherapy has been extensively used for chronic spontaneous urticaria in China. However, the evidence of its effectiveness and safety for the treatment of chronic spontaneous urticaria is insufficient. Hence, we conducted this study to compare auriculotherapy or auriculotherapy joint treatment with Western medicine for the cure of chronic spontaneous urticaria. This meta-analysis of seven randomized controlled trials showed that auriculotherapy or auriculotherapy joint treatment was significantly superior to Western medicine in curing clinical signs and symptoms of chronic spontaneous urticaria [odds ration (OR), 2.61; 95% confidence interval (CI), 1.54–4.43; p = 0.0004) and also better in total effect rate (OR, 3.81; 95% CI, 2.07–7.01; p<0.0001). But, auriculotherapy or auriculotherapy joint treatment was similar to Western medicine in improving clinical signs and symptoms of chronic spontaneous urticaria (OR, 0.74; 95% CI, 0.35–1.56; p = 0.42). Auriculotherapy or auriculotherapy joint treatment was safer than Western medicine for curing chronic spontaneous urticaria (OR, 0.26; 95% CI, 0.09–0.80; p = 0.02). Auriculotherapy alone or auriculotherapy joint treatment appears to be more effective and safer than Western medicine that contains antihistamines in the treatment of chronic spontaneous urticaria. However, these findings should be interpreted with caution due to the unclear risk bias of methodological quality, and further studies with large-scale, better, and more rigorously designed protocol are necessary to prove these findings. Keywords: auricular acupuncture, auriculotherapy, urticaria, review, meta-analysishttp://www.sciencedirect.com/science/article/pii/S2005290118300827
spellingShingle Libing Zhu
Yunjin Kim
Zongbao Yang
The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis
Journal of Acupuncture & Meridian Studies
title The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis
title_full The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis
title_fullStr The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis
title_full_unstemmed The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis
title_short The Application of Auriculotherapy to the Treatment of Chronic Spontaneous Urticaria: A Systematic Review and Meta-analysis
title_sort application of auriculotherapy to the treatment of chronic spontaneous urticaria a systematic review and meta analysis
url http://www.sciencedirect.com/science/article/pii/S2005290118300827
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