Experience in using immunal in the complex treatment of patients with torpid peptic ulcer
Aim. to provide a rationale for the use of immunal in intractable gastroduodenal peptic ulcers (PU), by studying Helicobacter pylori genotypes and immunological parameters. Subjects and methods. Sixty-eight patients (37 men and 31 women) with torpid PU were examined. A study group comprised 35 patie...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2010-02-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30534 |
| _version_ | 1818772808070594560 |
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| author | Yakov Maksimovich Vakhrushev Anvar Raifovich Balagatdinov Ya M Vakhrushev A R Balagatdinov |
| author_facet | Yakov Maksimovich Vakhrushev Anvar Raifovich Balagatdinov Ya M Vakhrushev A R Balagatdinov |
| author_sort | Yakov Maksimovich Vakhrushev |
| collection | DOAJ |
| description | Aim. to provide a rationale for the use of immunal in intractable gastroduodenal peptic ulcers (PU), by studying Helicobacter pylori genotypes and immunological parameters.
Subjects and methods. Sixty-eight patients (37 men and 31 women) with torpid PU were examined. A study group comprised 35 patients who took immunal as a component of complex eradication therapy; a control group included 33 patients who received complex eradication therapy only. In addition to clinical and endoscopic data, the values of H. pylori genotypes were used to evaluate therapeutic efficiency.
Results. The inclusion of immunal into the complex therapy in patients with torpid PU exerts a significant clinical effect in relieving the pain syndrome and dyspeptic symptoms and in accelerating ulcer cicatrization. The disappearance of virulent H. pylori strains was noted during treatment. Recovery of phagocytic, cellular, and humoral immunities is an important result of therapy.
Conclusion. The use of immunal as a component of complex therapy for torpid PU is pathogenetically founded and clinically effective. |
| first_indexed | 2024-12-18T10:15:14Z |
| format | Article |
| id | doaj.art-8bda1445397a4da596475c6e601fade1 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-18T10:15:14Z |
| publishDate | 2010-02-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-8bda1445397a4da596475c6e601fade12022-12-21T21:11:19Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422010-02-01822131727561Experience in using immunal in the complex treatment of patients with torpid peptic ulcerYakov Maksimovich VakhrushevAnvar Raifovich BalagatdinovYa M VakhrushevA R BalagatdinovAim. to provide a rationale for the use of immunal in intractable gastroduodenal peptic ulcers (PU), by studying Helicobacter pylori genotypes and immunological parameters. Subjects and methods. Sixty-eight patients (37 men and 31 women) with torpid PU were examined. A study group comprised 35 patients who took immunal as a component of complex eradication therapy; a control group included 33 patients who received complex eradication therapy only. In addition to clinical and endoscopic data, the values of H. pylori genotypes were used to evaluate therapeutic efficiency. Results. The inclusion of immunal into the complex therapy in patients with torpid PU exerts a significant clinical effect in relieving the pain syndrome and dyspeptic symptoms and in accelerating ulcer cicatrization. The disappearance of virulent H. pylori strains was noted during treatment. Recovery of phagocytic, cellular, and humoral immunities is an important result of therapy. Conclusion. The use of immunal as a component of complex therapy for torpid PU is pathogenetically founded and clinically effective.https://ter-arkhiv.ru/0040-3660/article/view/30534helicobacter pyloriintractable gastroduodenal ulcershelicobacter pyloriimmune systemimmunal |
| spellingShingle | Yakov Maksimovich Vakhrushev Anvar Raifovich Balagatdinov Ya M Vakhrushev A R Balagatdinov Experience in using immunal in the complex treatment of patients with torpid peptic ulcer Терапевтический архив helicobacter pylori intractable gastroduodenal ulcers helicobacter pylori immune system immunal |
| title | Experience in using immunal in the complex treatment of patients with torpid peptic ulcer |
| title_full | Experience in using immunal in the complex treatment of patients with torpid peptic ulcer |
| title_fullStr | Experience in using immunal in the complex treatment of patients with torpid peptic ulcer |
| title_full_unstemmed | Experience in using immunal in the complex treatment of patients with torpid peptic ulcer |
| title_short | Experience in using immunal in the complex treatment of patients with torpid peptic ulcer |
| title_sort | experience in using immunal in the complex treatment of patients with torpid peptic ulcer |
| topic | helicobacter pylori intractable gastroduodenal ulcers helicobacter pylori immune system immunal |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30534 |
| work_keys_str_mv | AT yakovmaksimovichvakhrushev experienceinusingimmunalinthecomplextreatmentofpatientswithtorpidpepticulcer AT anvarraifovichbalagatdinov experienceinusingimmunalinthecomplextreatmentofpatientswithtorpidpepticulcer AT yamvakhrushev experienceinusingimmunalinthecomplextreatmentofpatientswithtorpidpepticulcer AT arbalagatdinov experienceinusingimmunalinthecomplextreatmentofpatientswithtorpidpepticulcer |