Platelets and viruses
Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associa...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-04-01
|
| Series: | Platelets |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09537104.2021.1887842 |
| _version_ | 1797684149023145984 |
|---|---|
| author | Silvio Antoniak Nigel Mackman |
| author_facet | Silvio Antoniak Nigel Mackman |
| author_sort | Silvio Antoniak |
| collection | DOAJ |
| description | Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns. Platelets can be beneficial and/or detrimental during viral infections. They reduce blood-borne viruses by engulfing the free virus and presenting the virus to neutrophils. However, platelets can also enhance inflammation and tissue injury during viral infections. Here, we discuss the roles of platelets in viral infection. |
| first_indexed | 2024-03-12T00:25:19Z |
| format | Article |
| id | doaj.art-8bddbf41e3ec473187ffbeb6050cdc28 |
| institution | Directory Open Access Journal |
| issn | 0953-7104 1369-1635 |
| language | English |
| last_indexed | 2024-03-12T00:25:19Z |
| publishDate | 2021-04-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Platelets |
| spelling | doaj.art-8bddbf41e3ec473187ffbeb6050cdc282023-09-15T10:38:09ZengTaylor & Francis GroupPlatelets0953-71041369-16352021-04-0132332533010.1080/09537104.2021.18878421887842Platelets and virusesSilvio Antoniak0Nigel Mackman1University of North Carolina at Chapel HillUniversity of North Carolina at Chapel HillPlatelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns. Platelets can be beneficial and/or detrimental during viral infections. They reduce blood-borne viruses by engulfing the free virus and presenting the virus to neutrophils. However, platelets can also enhance inflammation and tissue injury during viral infections. Here, we discuss the roles of platelets in viral infection.http://dx.doi.org/10.1080/09537104.2021.1887842plateletsmyocarditisinfluenza a viruscoronavirus |
| spellingShingle | Silvio Antoniak Nigel Mackman Platelets and viruses Platelets platelets myocarditis influenza a virus coronavirus |
| title | Platelets and viruses |
| title_full | Platelets and viruses |
| title_fullStr | Platelets and viruses |
| title_full_unstemmed | Platelets and viruses |
| title_short | Platelets and viruses |
| title_sort | platelets and viruses |
| topic | platelets myocarditis influenza a virus coronavirus |
| url | http://dx.doi.org/10.1080/09537104.2021.1887842 |
| work_keys_str_mv | AT silvioantoniak plateletsandviruses AT nigelmackman plateletsandviruses |